Search results for: Young-Il Koh

Items from 1 to 14 out of 14 results

article

Treatable traits in the NOVELTY study

Alvar Agustí, Eleni Rapsomaniki, Richard Beasley, Rod Hughes, more

Background and objective Asthma and chronic obstructive pulmonary disease (COPD) are two prevalent and complex diseases that require personalized management. Although a strategy based on treatable traits (TTs) has been proposed, the prevalence and relationship of TTs to the diagnostic label and disease severity established by the attending physician in a real‐world setting are unknown. We assessed...

article

Characteristics of Specialist‐Diagnosed Asthma‐COPD Overlap in Severe Asthma: Observations from the Korean Severe Asthma Registry (KoSAR)

Hyun Lee, Sang‐Heon Kim, Byung‐Keun Kim, Youngsoo Lee, more

Allergy > 76 > 1 > 223 - 232

Background While the clinical characteristics and outcomes of asthma‐chronic obstructive pulmonary disease (COPD) overlap (ACO) have been frequently compared with those of COPD or asthma, the prevalence and features of ACO in patients with severe asthma are unclear. Objectives Evaluation of the prevalence and clinical features of ACO using the Korean severe asthma registry. Methods At the time...

article

The first case of tegoprazan‐induced urticaria

Da Woon Sim, Ji Eun Yu, Sun‐Young Park, Young‐Il Koh

Journal of Clinical Pharmacy and Therapeutics > 45 > 5 > 1187 - 1189

What is known and objective Tegoprazan induces adverse drug reactions during clinical trials; however, tegoprazan‐induced urticaria has not been reported. Here, we describe the first case of this. Case description A 55‐year‐old woman presented with acute urticaria with pruritus after taking the gastro‐oesophageal reflux disease medication, tegoprazan. Urticaria disappeared after tegoprazan discontinuation...

article

Variation of clinical manifestations according to culprit drugs in DRESS syndrome

Da Woon Sim, Ji Eun Yu, Jiung Jeong, Jae‐Woo Jung, more

Pharmacoepidemiology and Drug Safety > 28 > 6 > 840 - 848

Purpose Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a rare but serious condition that systematically damages various internal organs through T‐cell–mediated immunological drug reactions. We aimed to investigate whether clinical manifestations of DRESS syndrome differ according to culprit drugs. Methods We retrospectively analyzed data from 123 patients with probable/definite...

article

Clinical outcome and efficacy of current anti-leukemic therapy for leptomeningeal involvement in acute myeloid leukemia

Ji Hyun Kwon, Young-il Koh, Sung-soo Yoon, Seonyang Park, more

International Journal of Hematology > 2016 > 104 > 5 > 574-581

We investigated risk factors and outcome in acute myeloid leukemia (AML) patients with leptomeningeal involvement. Medical records of patients with non-promyelocytic AML at Seoul National University Hospital from January of 2000 to November of 2013 were reviewed. Leptomeningeal involvement was defined as the presence of atypical or malignant hematopoietic cells in the cerebrospinal fluid. Among 775...

article

A Case of Successful Treatment of Autoinflammatory Syndrome-Associated Chronic Urticaria with Anakinra

Young-Il Koh, Min-joo Ahn, Ji Eun Yu, Jiung Jeong

Journal of Allergy and Clinical Immunology > 2016 > 137 > 2(S) > AB246

article

Flagellin suppresses experimental asthma by generating regulatory dendritic cells and T cells

Jae-Uoong Shim, Shee Eun Lee, Won Hwang, Changhon Lee, more

Journal of Allergy and Clinical Immunology > 2016 > 137 > 2 > 426-435

Although the hygiene hypothesis suggests that microbial infections could subvert asthma and thus a microbial product might serve as a therapeutic adjuvant for asthma, the relationship between bacterial components and asthma is complex. Recently, low levels of flagellin, the Toll-like receptor (TLR) 5 ligand, have been reported to promote asthma.We show that a therapeutic dose of flagellin suppresses...

article

XXIV World Allergy Congress 2015

Heung-Man Lee, Il-Ho Park, Jae-Min Shin, Hyun-Sun Yoon, more

World Allergy Organization Journal > 2016 > 9 > 1 > 1-206

Table of Contents A1 Pirfenidone inhibits TGF-b1-induced extracellular matrix production in nasal polyp-derived fibroblasts Jae-Min Shin, Heung-Man Lee, Il-Ho Park A2 The efficacy of a 2-week course of oral steroid in the treatment of chronic spontaneous urticaria refractory to antihistamines Hyun-Sun Yoon, Gyeong Yul Park A3 The altered distribution of follicular t helper...

article

Increased Blood Th2-Like Invariant Natural Killer T Cells In Patients With Asthma

Young-Il Koh, Jae-Uoong Shim

The Journal of Allergy and Clinical Immunology > 2014 > 133 > 2 Supplement > AB86

article

Allergic contact stomatitis caused by a titanium nitride-coated implant abutment: A clinical report

Hyun-Pil Lim, Kwang-Min Lee, Young-Il Koh, Sang-Won Park

The Journal of Prosthetic Dentistry > 2012 > 108 > 4 > 209-213

A patient developed contact mucositis after being treated with a titanium nitride implant abutment. Patch testing disclosed a positive reaction to titanium nitride. After removal of the titanium nitride-coated abutment and placement of an uncoated abutment, all signs and symptoms disappeared. This clinical report suggests that titanium nitride-coated abutments may be a potential allergen in some patients.

article

Inverse association of peripheral blood CD4+ invariant natural killer T cells with atopy in human asthma

Young-Il Koh, Jae-Uoong Shim, Jeong-Ook Wi, Eui-Ryoung Han, more

Human Immunology > 2010 > 71 > 2 > 186-191

Invariant natural killer T (iNKT) cells have been reported to play a role in the pathogenesis of murine asthma. However, the role for iNKT cells in the pathogenesis of human asthma is not defined. In this study we aimed to determined how blood iNKT cells are associated with atopy in asthmatic individuals. Peripheral blood mononuclear cells were isolated from 45 asthmatic subjects. iNKT cells were...

article

The relation between epithelial proliferation and airway obstruction after ozone exposure

An-Soo Jang, Inseon S Choi, Young-Il Koh

The Journal of Allergy and Clinical Immunology > 2002 > 109 > 1 Supplement 1 > S52

article

Relationship between changes in interferon-gamma production by peripheral blood T-cells and changes in peak expiratory flow rate in patients with chronic stable asthma

Young-Il Koh, Inseon S Choi

The Journal of Allergy and Clinical Immunology > 2002 > 109 > 1 Supplement 1 > S27

article

Outdoor air pollutants derived from industrial processes may be causally related to the development of asthma in children

Yoon-Keun Kim, Domyung Baek, Young-Il Koh, Sang-Heon Cho, more

Annals of Allergy, Asthma & Immunology > 2001 > 86 > 4 > 456-460

There is no consistent evidence that outdoor air pollutants are involved in the development of asthma. The aim of this study was to determine whether outdoor air pollutants derived from industrial processes were related to the prevalence of asthma, bronchial hyperresponsiveness, and atopy in exposed children. A total of 7,511 children from 7 to 12 years of age were recruited in the study. Eight...

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