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Amyloid-β (Aβ) is a naturally occurring 40- or 42-residue peptide fragment with a primary role in Alzheimer's disease (AD). Aggregated Aβ accumulates as both dense core plaques and diffuse deposits in the brains of AD patients. Aβ plaques are surrounded by activated microglia, some of which are believed to be derived from peripheral blood monocytes that have infiltrated the central nervous system...