Search results for: Xuening Chen

Items from 1 to 20 out of 22 results

article

Coupling BCP Ceramics with Micro‐Vibration Stimulation Field for Cascade Amplification from Immune Activation to Bone Regeneration

Jinjie Wu, Menglu Wang, Yuehao Wu, Jiajun Liu, more

Advanced Functional Materials > 33 > 24 > n/a - n/a

The osteoimmunology has revealed that immune system plays an important role in maintaining bone metabolism and remodeling. As long‐term physiological factor in bone, mechanical stimulation such as micro‐vibration stimulation (MVS) exerts effects on regulating osteogenesis and immune response. In this study, the osteo‐immunodulatory effects of bicalcium phosphate (BCP) ceramics coupled with MVS are...

article

The effects of tea polyphenol‐ozonated slurry ice treatment on the quality of large yellow croaker (Pseudosciaena crocea) during chilled storage

Weiqing Lan, Xuening Chen, Yanan Zhao, Jing Xie

Journal of the Science of Food and Agriculture > 102 > 15 > 7052 - 7061

BACKGROUND The aim of the current study was to evaluate the synergistic effects of tea polyphenol‐ozonated slurry ice on the quality, physicochemical and protein characteristics of large yellow croaker (Pseudosciaena crocea) during chilled (4 °C) storage. To 0.3% tea polyphenol combined with ozone water was added sodium chloride until the salt concentration reached 3.3% and with the use of an ice...

article

Insights into the antibacterial mechanism of ozone water combined with tea polyphenols against Shewanella putrefaciens: membrane disruption and oxidative stress

Weiqing Lan, Xuening Chen, Yanan Zhao, Jing Xie

International Journal of Food Science & Technology > 57 > 11 > 7423 - 7433

Shewanella putrefaciens (S. putrefaciens) is the main specific spoilage organism (SSO) of marine fish during cold logistic process. To explore the antimicrobial mechanism of ozone water combined with tea polyphenol (TP) against S. putrefaciens, the growth condition, endogenous oxidative stress, changes of membrane integrity and energy metabolism enzyme were evaluated, respectively. As evidenced by...

article

Enhancing mechanical and biological properties of biphasic calcium phosphate ceramics by adding calcium oxide

Yuyi Wang, Menglu Wang, Fuying Chen, Cong Feng, more

Journal of the American Ceramic Society > 104 > 1 > 548 - 563

There is a big challenge to achieve a balance between mechanical characteristics and biological properties in biphasic calcium phosphate (BCP) ceramics. The present study investigated the effects of calcium oxide (CaO) addition on the sintering behaviors and biological performances of BCP ceramics. The characterizations of surface structure, phase composition and crystal structure demonstrated that...

article

Improved LSH for privacy-aware and robust recommender system with sparse data in edge environment

Xuening Chen, Hanwen Liu, Dan Yang

EURASIP Journal on Wireless Communications and Networking > 2019 > 2019 > 1 > 1-11

Recommender systems have become a popular and effective way to quickly discover new service items that are probably preferred by prospective users. Through analyzing the historical service usage data produced in the past, a recommender system can infer the potential user preferences and make accurate recommendations accordingly. However, in the edge environment, the service usage data stored in each...

article

LSH-based private data protection for service quality with big range in distributed educational service recommendations

Chao Yan, Xuening Chen, Qinglei Kong

EURASIP Journal on Wireless Communications and Networking > 2019 > 2019 > 1 > 1-9

Service recommendation has become a promising way to extract useful or valuable information from big educational data collected by various sensors and distributed in different platforms. How to protect the private user data in each cluster during recommendation processes is an interesting but challenging problem in the educational domain. A locality-sensitive hashing (LSH) technique has recently been...

article

Fabrication and preliminary biological evaluation of a highly porous biphasic calcium phosphate scaffold with nano-hydroxyapatite surface coating

Jing Wang, Yu Zhu, Menglu Wang, Dan Liu, more

Ceramics International > 2018 > 44 > 2 > 1304-1311

Considering that the structure of scaffold determines its functionality, in this study biphasic calcium phosphate (BCP) scaffold with highly interconnected macroporous structure was firstly fabricated by a polymeric sponge replication method, in which a ethanol solution (25vol%) was use for preparation of the slurry and a varying slurry viscosity during multiple impregnations was adopted. Then, the...

article

Selective effect of hydroxyapatite nanoparticles on osteoporotic and healthy bone formation correlates with intracellular calcium homeostasis regulation

Rui Zhao, Pengfei Xie, Kun Zhang, Zhurong Tang, more

Acta Biomaterialia > 2017 > 59 > C > 338-350

Adequate bone substitutes osseointegration has been difficult to achieve in osteoporosis. Hydroxyapatite of the osteoporotic bone, secreted by pathologic osteoblasts, had a smaller crystal size and lower crystallinity than that of the normal. To date, little is known regarding the interaction of synthetic hydroxyapatite nanoparticles (HANPs) with osteoblasts born in bone rarefaction. The present study...

article

Role of biphasic calcium phosphate ceramic-mediated secretion of signaling molecules by macrophages in migration and osteoblastic differentiation of MSCs

Jing Wang, Dan Liu, Bo Guo, Xiao Yang, more

Acta Biomaterialia > 2017 > 51 > C > 447-460

The inflammatory reaction initiates fracture healing and could play a role in the osteoinductive effect of calcium phosphate (CaP) ceramics, which has been widely confirmed; however, the underlying mechanism has not been fully elucidated. In this study, various signaling molecules from macrophages under the stimulation of osteoinductive biphasic calcium phosphate (BCP) ceramic and its degradation...

article

A multi-level comparative analysis of human femoral cortical bone quality in healthy cadavers and surgical safe margin of osteosarcoma patients

Xuelei Zhang, Zhurong Tang, Yong Zhou, Xuening Chen, more

Journal of the Mechanical Behavior of Biomedical Materials > 2017 > 66 > C > 111-118

Osteosarcoma is the most common primary malignancy of bone. However, the potential variation it brings to the adjacent undamaged bone tissue is seldom investigated. In this study, we conducted a multi-level comparison of human femoral cortical bone quality in healthy cadavers (aged 42±11 years) and in resected safe margin of osteosarcoma patients (aged 49±15 years). The objective of this study was...

article

Regulation of the secretion of immunoregulatory factors of mesenchymal stem cells (MSCs) by collagen-based scaffolds during chondrogenesis

Jingyu Yang, Xuening Chen, Tun Yuan, Xiao Yang, more

Materials Science and Engineering: C > 2017 > 70 > P2 > 983-991

In the latest decade, mesenchymal stem cells (MSCs) have wildly considered as a source of seeded cells in tissue engineering, not only because of its multi-differentiation potentials, but also due to its immunoregulation ability. The main immunoregulatory features of MSCs could be divided into low self-immunogenicity and secretion of soluble factors. In this study, we explored how scaffold structures...

article

Comparison of ectopic bone formation process induced by four calcium phosphate ceramics in mice

Zhurong Tang, Yanfei Tan, Yilu Ni, Jing Wang, more

Materials Science and Engineering: C > 2017 > 70 > P2 > 1000-1010

Phase composition played a key role in the biodegradation of calcium phosphate ceramics (CaP), which in turn influences the osteoinductive ability. The in vivo biological mechanism is still poorly understood. In this study, four types of porous CaP ceramics were investigated, namely, hydroxyapatite (HA), β-tricalcium phosphate (TCP), and biphasic calcium phosphates BCP1 and BCP2, with HA to β-TCP...

article

Gelatinizing technology combined with gas foaming to fabricate porous spherical hydroxyapatite bioceramic granules

Xiangfeng Li, Yanglong Deng, Xuening Chen, Yumei Xiao, more

Materials Letters > 2016 > 185 > C > 428-431

This study fabricated porous spherical hydroxyapatite (HA) bioceramic granules via a novel method by combining the ionotropic gelation of sodium alginate with H₂O₂ gas-foaming. Firstly, HA powder was dispersed in sodium alginate solution; then, the bubbly slurry prepared by H₂O₂ gas-foaming was dripped into CaCl₂ solution to form hydrogel spheres; finally, these hydrogel spheres were washed, dried...

article

Administration duration influences the effects of low‐magnitude, high‐frequency vibration on ovariectomized rat bone

Fangzhu Qing, Pengfei Xie, Yacincha Selushia Liem, Ying Chen, more

Journal of Orthopaedic Research® > 34 > 7 > 1147 - 1157

Low‐magnitude, high‐frequency vibration (LMHFV) has been proposed as a non‐drug anti‐osteoporosis treatment. However, the influence of administration duration on its effect is seldom investigated. In this study, the effect of 16‐week LMHFV (0.3 g, 30 Hz, 20 min/day) on the bone mineral densities (BMDs), bone mechanical properties, and cellular responses of osteoporotic and healthy rats was examined...

article

Bone mineral density, microarchitectural and mechanical alterations of osteoporotic rat bone under long-term whole-body vibration therapy

Pengfei Xie, Zhurong Tang, Fangzhu Qing, Xuening Chen, more

Journal of the Mechanical Behavior of Biomedical Materials > 2016 > 53 > C > 341-349

Low-magnitude, high-frequency whole body vibration (WBV) is receiving increasing interest as a non-pharmacological anti-osteoporosis approach. However, the long-term effect of WBV therapy is seldom studied. In this study, the efficacy of 16-week WBV (0.3g, 30Hz) on bone mineral density (BMD), microarchitectural parameters and mechanical properties of ovariectomized rat femur were examined by in vivo...

article

Mechanical and biological properties of the micro-/nano-grain functionally graded hydroxyapatite bioceramics for bone tissue engineering

Changchun Zhou, Congying Deng, Xuening Chen, Xiufen Zhao, more

Journal of the Mechanical Behavior of Biomedical Materials > 2015 > 48 > C > 1-11

Functionally graded materials (FGM) open the promising approach for bone tissue repair. In this study, a novel functionally graded hydroxyapatite (HA) bioceramic with micrograin and nanograin structure was fabricated. Its mechanical properties were tailored by composition of micrograin and nanograin. The dynamic mechanical analysis (DMA) indicated that the graded HA ceramics had similar mechanical...

article

Shell-core bi-layered scaffolds for engineering of vascularized osteon-like structures

Xuening Chen, Asli Ergun, Halil Gevgilili, Seher Ozkan, more

Biomaterials > 2013 > 34 > 33 > 8203-8212

Bottom-up assembly of osteon-like structures into large tissue constructs represents a promising and practical strategy toward the formation of hierarchical cortical bone. Here, a unique two-step approach, i.e., the combination of electrospinning and twin screw extrusion (TSE) techniques was used to fabricate a microfilament/nanofiber shell–core scaffold that could precisely control the spatial distribution...

article

Regulation of the osteogenesis of pre-osteoblasts by spatial arrangement of electrospun nanofibers in two- and three-dimensional environments

Xuening Chen, Xiaoling Fu, Jian-gang Shi, Hongjun Wang

Nanomedicine: Nanotechnology, Biology, and Medicine > 2013 > 9 > 8 > 1283-1292

Orientation of extracellular matrix (ECM) fibrils contributes to the anisotropy of bones, but little is known about how fibril orientation induces osteoblastic responses. Here, biomimetic polycaprolactone/type I collagen (PCL/COL-1) nanofibers with aligned and random fiber arrangements were used as models to study their effects on pre-osteoblasts. Elongated cell morphology, accelerated cell migration,...

article

Inkjet printed antibiotic- and calcium-eluting bioresorbable nanocomposite micropatterns for orthopedic implants

Yexin Gu, Xuening Chen, Joung-Hyun Lee, David A. Monteiro, more

Acta Biomaterialia > 2012 > 8 > 1 > 424-431

Inkjet printing of antibiotic- and calcium-eluting micropatterns was explored as a novel means of preventing the formation of biofilm colonies and facilitating osteogenic cell development on orthopedic implant surfaces. The micropatterns consisted of a periodic array of ∼50μm circular dots separated by ∼150μm. The composition of the micropatterns was controlled by formulating inks with rifampicin...

article

Acceleration of Osteogenic Differentiation of Preosteoblastic Cells by Chitosan Containing Nanofibrous Scaffolds

Xiaochuan Yang, Xuening Chen, Hongjun Wang

Biomacromolecules > 2009 > 10 > 10 > 2772 - 2778

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Search results for: Xuening Chen

Coupling BCP Ceramics with Micro‐Vibration Stimulation Field for Cascade Amplification from Immune Activation to Bone Regeneration

The effects of tea polyphenol‐ozonated slurry ice treatment on the quality of large yellow croaker (Pseudosciaena crocea) during chilled storage

Insights into the antibacterial mechanism of ozone water combined with tea polyphenols against Shewanella putrefaciens: membrane disruption and oxidative stress

Enhancing mechanical and biological properties of biphasic calcium phosphate ceramics by adding calcium oxide

Improved LSH for privacy-aware and robust recommender system with sparse data in edge environment

LSH-based private data protection for service quality with big range in distributed educational service recommendations

Fabrication and preliminary biological evaluation of a highly porous biphasic calcium phosphate scaffold with nano-hydroxyapatite surface coating

Selective effect of hydroxyapatite nanoparticles on osteoporotic and healthy bone formation correlates with intracellular calcium homeostasis regulation

Role of biphasic calcium phosphate ceramic-mediated secretion of signaling molecules by macrophages in migration and osteoblastic differentiation of MSCs

A multi-level comparative analysis of human femoral cortical bone quality in healthy cadavers and surgical safe margin of osteosarcoma patients

Regulation of the secretion of immunoregulatory factors of mesenchymal stem cells (MSCs) by collagen-based scaffolds during chondrogenesis

Comparison of ectopic bone formation process induced by four calcium phosphate ceramics in mice

Gelatinizing technology combined with gas foaming to fabricate porous spherical hydroxyapatite bioceramic granules

Administration duration influences the effects of low‐magnitude, high‐frequency vibration on ovariectomized rat bone

Bone mineral density, microarchitectural and mechanical alterations of osteoporotic rat bone under long-term whole-body vibration therapy

Mechanical and biological properties of the micro-/nano-grain functionally graded hydroxyapatite bioceramics for bone tissue engineering

Shell-core bi-layered scaffolds for engineering of vascularized osteon-like structures

Regulation of the osteogenesis of pre-osteoblasts by spatial arrangement of electrospun nanofibers in two- and three-dimensional environments

Inkjet printed antibiotic- and calcium-eluting bioresorbable nanocomposite micropatterns for orthopedic implants

Acceleration of Osteogenic Differentiation of Preosteoblastic Cells by Chitosan Containing Nanofibrous Scaffolds

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