Search results for: Karl L. Kiening

Items from 1 to 9 out of 9 results

article

Accuracy and revision rate of intraoperative computed tomography point-to-point navigation for lateral mass and pedicle screw placement: 11-year single-center experience in 1054 patients

Basem Ishak, Alexander Younsi, Carola Wieckhusen, Paula Slonczewski, more

Neurosurgical Review > 2019 > 42 > 4 > 895-905

High accuracy in intraoperative computed tomography (iCT) navigation utilizing an intraoperatively acquired dataset for screw placement in the spine has been reported in the literature. To further improve the accuracy and counteract any intraoperative movement of predefined registration points, we introduce an iCT point-to-point navigation, where marker screws are inserted intraoperatively to increase...

article

Modified Posterior C1 Lateral Mass Screw Insertion for Type II Odontoid Process Fractures Using Intraoperative Computed Tomography–Based Spinal Navigation to Minimize Postoperative Occipital Neuralgia

Basem Ishak, Till Schneider, R. Shane Tubbs, Valerie Gimmy, more

World Neurosurgery > 2017 > 107 > C > 194-201

Various surgical techniques have been described for treating odontoid instability and achieving effective stabilization. The earliest technique to be described proposed a C1 lateral mass entry point including neurectomy of the C2 nerve roots to ensure hemostasis. Because C2 neurectomy remains controversial, preservation of the C2 nerve root as described in Goel-Harms technique can lead to intractable...

chapter

Zerebrales und neurophysiologisches Monitoring

Karl L. Kiening, Asita Simone Sarrafzadeh-Khorassani

Klinikmanual Intensivmedizin > Diagnostik und Überwachung > 43-47

Eine zerebrale Hypoxie bzw. Ischämie, z. B. durch arterielle Hypoxämie, Blutdruckabfall oder intrakranielle Drucksteigerung, erhöht bei zerebral geschädigten Patienten das Risiko sekundärer Hirnschäden und verschlechtert dadurch das klinische Ergebnis oder Outcome.

chapter

Zerebrales Monitoring, neurophysiologisches Monitoring

Karl L. Kiening, Asita Simone Sarrafzadeh

Die Intensivmedizin > Diagnostik und Überwachung > 181-187

article

One ring to rule them all? – Temporospatial specificity of deep brain stimulation for treatment-resistant depression

Carolin Hoyer, Alexander Sartorius, Lucas Lecourtier, Karl L. Kiening, more

Medical Hypotheses > 2013 > 81 > 4 > 611-618

Deep brain stimulation (DBS) for intractable cases of depression has emerged as a valuable therapeutic option during the last decade. While several locations have been intensely investigated in recent years, the literature is lacking an all-encompassing perspective thereupon asking if and how these stimulation sites relate to each other and what this may imply for the underlying mechanisms of action...

article

Anticonvulsive effects of the dopamine agonist lisuride maleate after experimental traumatic brain injury

Klaus Zweckberger, Filip Simunovic, Karl L. Kiening, Andreas W. Unterberg, more

Neuroscience Letters > 2010 > 470 > 2 > 150-154

Traumatic brain injury is a heterogeneous disease, encompassing a wide range of pathologies. The dopamine agonist lisuride is well established in the therapy of Parkinson's disease. Additionally to its dopaminergic effects it decreases prolactine release, reducing the amount of inflammatory mediators such as TNF-α or Il-6. Lisuride has strong binding affinity to serotonergic and histaminergic receptors...

article

Remission of Major Depression Under Deep Brain Stimulation of the Lateral Habenula in a Therapy-Refractory Patient

Alexander Sartorius, Karl L. Kiening, Peter Kirsch, Carl C. von Gall, more

Biological Psychiatry > 2010 > 67 > 2 > e9-e11

article

Neuromonitoring: Brain oxygenation and microdialysis

Asita S. Sarrafzadeh, Karl L. Kiening, Andreas W. Unterberg

Current Neurology and Neuroscience Reports > 2003 > 3 > 6 > 517-523

Patients with cerebral lesions run a high risk of developing cerebral hypoxic and ischemic damage due to secondary insults. To minimize the risk of secondary cerebral hypoxia and ischemia, new monitoring techniques of cerebral oxygenation and metabolism have been developed and may help to understand the pathophysiology of secondary brain damage for a better treatment and outcome in critical patients...

article

Decreased hemispheric Aquaporin-4 is linked to evolving brain edema following controlled cortical impact injury in rats

Karl L. Kiening, Frank K.H. van Landeghem, Stefan Schreiber, Ulrich W. Thomale, more

Neuroscience Letters > 2002 > 324 > 2 > 105-108

The cerebral Aquaporin-4 (AQP4) water channel is suggested to be involved in brain edema formation aggravated by reduced cerebral blood flow early after traumatic brain injury (TBI). Therefore, the temporal profile of brain edema formation, AQP4 expression, and cortical perfusion were investigated following focal TBI in rats. Brain edema was maximal by 24 h. Concurrently, AQP4 protein expression was...

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