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Human leukocyte antigen (HLA)‐G molecule acts as a potential factor for the regulation of immune responses and its expression in virus‐infected cells may enable them to escape immunosurveillance. Besides its polymorphic promoter region, the 3′ untranslated region (UTR) seems to play an important role in regulating HLA‐G expression. In this study, we investigated the influence of HLA‐G 14 bp (rs66554220)...
In Japanese, Koreans and Caucasians, narcolepsy/hypocretin deficiency is tightly associated with the DRB1*15:01‐DQA1*01:02‐DQB1*06:02 haplotype. Studies in African‐Americans suggest a primary effect of DQB1*06:02, but this observation has been difficult to confirm in other populations because of high linkage disequilibrium between DRB1*15:01/3 and DQB1*06:02 in most populations. In this study, we...
CD1 molecules are the major histocompatibility complex (MHC)‐like glycoproteins specialized in capturing and presenting a variety of glycolipid to antigen‐specific T‐cells. There are five closely linked CD1 genes termed as CD1a, CD1b, CD1c, CD1d, and CD1e. CD1 gene features limited the polymorphism in exon 2 which encodes for the α1 domain. Few investigations on the allele frequencies of the CD1 genes...
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