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To evaluate the relative accuracy of contrast-enhanced time-resolved angiography with interleaved stochastic trajectories versus conventional contrast-enhanced magnetic resonance imaging (MRI) following International Society for the Study of Vascular Anomalies updated 2014-based classification of soft-tissue vascular anomalies in the head and neck in children.Time-resolved angiography with interleaved...
Three different silver metal nanobox arrays are used to demonstrate plasmon-enhanced non-radiative energy transfer from an InGaN/GaN quantum well to a ∼80 nm thick layer of CdSe/ZnS quantum dots embedded in PMMA. These arrays of varying periodicity are fabricated using helium-ion lithography. Whilst no direct signatures of non-radiative energy transfer are detected in the absence of the Ag nanobox...
We have previously shown that a novel non-viral gene delivery system (VIPER) composed of FDA-approved agents (2% lipiodol, 5.5% iopamidol, and 50:1 protamine:plasmid DNA) can selectively transfect hepatocellular carcinoma (HCC). In this study we test the hypothesis that VIPER utilizes receptor-mediated endocytosis (RME) and subsequent lysosomal trafficking to gain access to intracellular components,...
To demonstrate effective gene delivery to hepatocytes and selectivity toward hepatoma cells using high throughput screening of a library of biodegradable, non-toxic poly(beta-amino ester) (PBAE) nanoparticle (NP) delivery vehicles.PBAEs were synthesized per established protocols. eGFP reporter DNA was used for in vitro transfection of rat hepatoma cells (MCA-RH7777) and hepatocytes (BRL-3A). NPs were...
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