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Platinum-based neoadjuvant chemotherapy (NAC) improves overall survival in muscle-invasive bladder cancer (MIBC). A pathological complete response (pCR) at radical cystectomy after NAC is associated with better overall survival, but there are no established predictive biomarkers of response to NAC in MIBC. The aim of this study was to find laboratory variables associated with pCR following NAC.We...
The culture of human cells and tissues has become an established discipline since the pioneering work of individuals like Carrel, Hayflick, Gey and Ham (Freshney 3rd edition 1994). Our first edition chapter concentrated on qualitative and biochemical approaches to the use of invitro culture to study human pathology and in particular cancer. This edition describes molecular and new microscopic approaches...
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