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Background
Ovochymase 2 (Ovch2) is an epididymis‐specific gene that is required for male fertility. While a multitude of reproductive tract‐specific genes required for male fertility have been identified, OVCH2 is thus far the first protein required for male fertility that contains Complement C1r/C1s, Uegf, Bmp1 (CUB) domains located in tandem in the C‐terminus of the protein. Identifying the functional...
Background
The importance of phosphorylation in sperm during spermatogenesis has not been pursued extensively. Testis‐specific serine kinase 3 (Tssk3) is a conserved gene, but TSSK3 kinase functions and phosphorylation substrates of TSSK3 are not known.
Objective
The goals of our studies were to understand the mechanism of action of TSSK3.
Materials and methods
We analyzed the localization of...
The aim of this study was to determine whether short-term, in vivo exposure to silver nanoparticles (AgNPs) could be toxic to male reproduction. Low dose (1mg/kg/dose) AgNPs were intravenously injected into male CD1 mice over 12 days. Treatment resulted in no changes in body and testis weights, sperm concentration and motility, fertility indices, or follicle-stimulating hormone and luteinizing hormone...
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