Search results for: Ricardo C. Cavalli

Items from 1 to 20 out of 22 results

article

Glutamatergic and neural dysfunction in postpartum depression using magnetic resonance spectroscopy

Carlos E. Rosa, Jair C. Soares, Felipe P. Figueiredo, Ricardo C. Cavalli, more

Psychiatry Research: Neuroimaging > 2017 > 265 > C > 18-25

Although postpartum depression (PPD) is a prevalent subtype of major depressive disorder, neuroimaging studies on PPD are rare, particularly those identifying neurochemical abnormalities obtained by proton magnetic resonance spectroscopy (¹H-MRS). The dorsolateral prefrontal (DLPF) and the anterior cingulate gyrus (ACG) are part of the neural pathways involved in executive functions and emotional...

article

Positive correlations between circulating adiponectin and MMP2 in preeclampsia pregnant

Nibia Mariana Eleuterio, Ana C.T. Palei, Jackeline S. Rangel Machado, Jose E. Tanus-Santos, more

Pregnancy Hypertension: An International Journal of Women's Cardiovascular... > 2015 > 5 > 2 > 205-208

The aims of the present study were to compare plasma concentrations of the adiponectin, leptin, metalloproteinases (MMP9 and MMP2) and its tissue inhibitors (TIMP1 and TIMP2) in preeclamptic (PE) and healthy pregnant (HP) groups and correlate them.A total of 105 pregnant women with pre-pregnancy body mass index (BMI) values ⩽30kg/m ² were enrolled for this study (59 PE and 46 HP). Biomarkers...

article

Correlations among antiangiogenic factors and trace elements in hypertensive disorders of pregnancy

Vania B. Rezende, Fernando Barbosa, Ana C. Palei, Ricardo C. Cavalli, more

Journal of Trace Elements in Medicine and Biology > 2015 > 29 > Complete > 130-135

Although a number of studies have measured circulating levels of some trace elements in preeclampsia (PE) and compared to healthy pregnant (HP), there is no consensus yet about the deficiency of some metals and development of hypertensive disorders in pregnancy. The aim of this study was to compare plasmatic levels of Zn, Mn, Co, Cu, Se and Sr among non-pregnant (NP), healthy pregnant (HP), gestational...

article

Influence of type 2 diabetes mellitus on the pharmacokinetics and placental transfer of nifedipine in hypertensive pregnancy women

Ricardo C. Cavalli, Gabriela G. Filgueira, Vera L. Lanchote, Osmani O. Filgueira, more

Pregnancy Hypertension: An International Journal of Women's Cardiovascular... > 2015 > 5 > 1 > 122-123

Nifedipine is a dihydropyridine calcium channel blocker used in treatment of hypertension in pregnant women. The objective of the present study was to investigate the influence of T2DM on the pharmacokinetics and the placental transfer of nifedipine in hypertensive pregnant women.Twelve hypertensive pregnant women (HP) and ten hypertensive pregnant women with T2DM (HDP) taking oral slow-release nifedipine...

article

Risk factors influencing the development of hypertension in pregnancy in a convenience cohort

Luiz Augusto B. Martins, Marcos M. Okido, Marco A. Barbieri, Viviane C. Cardoso, more

Pregnancy Hypertension: An International Journal of Women's Cardiovascular... > 2015 > 5 > 1 > 121

Gestational hypertension and pre-eclampsia are important causes of perinatal morbidity. In this study we propose to study pregnant women between 20 and 25 weeks of gestation to evaluate the increase in relative risk for developing gestational hypertensive disorders, and correlating the findings with pregnancy outcome.This was a prospective cohort study of convenience. A total of 1417 patients in this...

article

Influence of a physiotherapy protocol in maternal and fetal hemodynamics in pregnant women with preeclampsia

Tawana V. Bertagnolli, Michelle S. Machado, Jackeline S. Machado, Cristine H. Ferreira, more

Pregnancy Hypertension: An International Journal of Women's Cardiovascular... > 2015 > 5 > 1 > 79

Pregnant women with preeclampsia, due to the complexity of the clinical frame remains at rest and such conduct leads to muscle discomfort, but no studies proving the safety and effectiveness of physical therapy protocols to improve such discomforts. To evaluate the influence of a physical therapy protocol applied in pregnant women with preeclampsia in relation to maternal and fetal hemodynamicsThe...

article

Assessment of quality of life of women with preeclampsia compared with healthy pregnant women

Michelle S. Machado, Tawana Vicente Bertagnolli, Jackeline S. Machado, Cristine H. Ferreira, more

Pregnancy Hypertension: An International Journal of Women's Cardiovascular... > 2015 > 5 > 1 > 120-121

Pre-eclampsia, that affects 2–3% of pregnancies worldwide and develops after the twenty week of pregnancy, is characterized by increased blood pressure and proteinuria. When the worsening of the clinical frame occurs, the admission of these women, which can lead to a change in quality of life is recommended. To evaluate the quality of life of women with preeclampsia and healthy pregnant women hospitalized...

article

Relationship of uterine artery flow in the second trimester of pregnancy with the neurodevelopment of children in the second year of life – A cohort study

Marcos M. Okido, Luiz Augusto B. Martins, Tawana V. Bertagnolli, Marco A. Barbieri, more

Pregnancy Hypertension: An International Journal of Women's Cardiovascular... > 2015 > 5 > 1 > 125

The association between increased resistance to flow in the uterine artery and adverse pregnancy outcomes has been demonstrated, but there are no studies evaluating their relationship with outcomes after birth. Our aim was to evaluate the relationship of the pulsatility index of the uterine artery in the second trimester of pregnancy with the neurodevelopment of children in the second year of life...

article

Assessment of concentrations of sFlt-1 and PlGF as predictors of preeclampsia

Jackeline S. Machado, Michelle S. Machado, Tawana V. Bertagnolli, Geraldo Duarte, more

Pregnancy Hypertension: An International Journal of Women's Cardiovascular... > 2015 > 5 > 1 > 58

Recent studies have shown that inadequate vascularization of the placenta may be caused by changes in the concentration of anti-angiogenic and pro-angiogenic factors like sFlt-1 and PlGF in maternal circulation indicating that they play an important role in the pathophysiology of preeclampsia. This study aimed evaluate the potential of sFlt-1 and PlGF as predictors of preeclampsia.We studied 50 healthy...

article

Antihypertensive therapy in preeclampsia is not modulated by VEGF polymorphisms

Valeria C. Sandrim, Ana C. T. Palei, Nibia Eleuterio, Jose E. Tanus-Santos, more

Archives of Gynecology and Obstetrics > 2015 > 291 > 4 > 799-803

Introduction Vascular endothelial growth factor (VEGF) is relevant for healthy pregnancy, and abnormalities in VEGF functions have been associated with hypertensive disorders of pregnancy. Our group recently demonstrated that VEGF genetic polymorphisms affect the susceptibility to preeclampsia (PE). Objective Therefore, in this study our aim is to examine whether VEGF ...

article

Relationship between adiponectin and nitrite in healthy and preeclampsia pregnancies

Nibia Mariana Eleuterio, Ana C.T. Palei, Jackeline S. Rangel Machado, Jose E. Tanus-Santos, more

Clinica Chimica Acta > 2013 > 423 > Complete > 112-115

Controversial results have been reported regarding plasma adiponectin levels in preeclampsia (PE) compared to healthy pregnancies (HP). Adiponectin activates eNOS, increasing the levels of the vasodilator nitric oxide (NO). PE reduces the levels of nitrite (an NO marker) and induces higher levels of ADMA (an endogenous eNOS inhibitor) compared to HP. No previous study has examined whether a positive...

article

Effects of Matrix Metalloproteinase (MMP)‐2 Polymorphisms on Responsiveness to Antihypertensive Therapy of Women with Hypertensive Disorders of Pregnancy

Ana C.T. Palei, Valeria C. Sandrim, Lorena M. Amaral, Jackeline S. R. Machado, more

Basic & Clinical Pharmacology & Toxicology > 111 > 4 > 262 - 267

Imbalanced matrix metalloproteinase (MMP) expression, including MMP‐2, has been demonstrated in pre‐eclampsia. However, little is known about the effect of polymorphisms in MMP‐2 gene on hypertensive disorders of pregnancy. We examined whether two functional MMP‐2 polymorphisms (g.‐1306C>T and g.‐735C>T) are associated with pre‐eclampsia and/or gestational hypertension and whether these polymorphisms...

article

Association between matrix metalloproteinase (MMP)-2 polymorphisms and MMP-2 levels in hypertensive disorders of pregnancy

Ana C.T. Palei, Valeria C. Sandrim, Lorena M. Amaral, Jackeline S.R. Machado, more

Experimental and Molecular Pathology > 2012 > 92 > 2 > 217-221

We examined whether two functional polymorphisms (g.-1306C>T and g.-735C>T) in matrix metalloproteinase (MMP)-2 gene are associated with preeclampsia (PE) or gestational hypertension (GH), and whether they modify MMP-2 or tissue inhibitor of metalloproteinase (TIMP)-2 plasma concentrations in these hypertensive disorders of pregnancy. We studied 130 healthy pregnant (HP), 130 pregnant with GH,...

article

Vitamin D receptor polymorphisms in hypertensive disorders of pregnancy

Vania B. Rezende, Valeria C. Sandrim, Ana C. Palei, Lorena Machado, more

Molecular Biology Reports > 2012 > 39 > 12 > 10903- 10906

Hypertension is the most common medical disorder in pregnancy, and a leading cause of maternal and neonatal morbidity and mortality. Vitamin D endocrine system has important influence on immune modulation and endothelial function, which play a role in preeclampsia (PE) and gestational hypertension (GH). Vitamin D receptor (VDR) is present in a large variety of cell types, including placental cells...

article

Alterations in cyclic GMP levels in preeclampsia may reflect increased B-type natriuretic peptide levels and not impaired nitric oxide activity

Valeria C. Sandrim, Ana C.T. Palei, Jonas T. Sertório, Lorena M. Amaral, more

Clinical Biochemistry > 2011 > 44 > 12 > 1012-1014

We compared nitrite, B-type natriuretic peptide (BNP), and cGMP levels in preeclamptic with those found in healthy pregnant.We studied 21 healthy pregnant and 27 preeclamptic. Plasma cGMP and BNP levels were determined by ELISA. Nitrite levels were determined by chemiluminescence.Higher cGMP and BNP, and lower nitrite levels were found in preeclamptic versus healthy pregnant.Altered cGMP levels reflect...

article

Changes in Fetal and Maternal Doppler Parameters Observed During Acute Severe Hypertension Treatment with Hydralazine or Labetalol: A Randomized Controlled Trial

Maria Rita F. Baggio, Wellington P. Martins, Ana Carolina S. Calderon, Aderson T. Berezowski, more

Ultrasound in Medicine & Biology > 2011 > 37 > 1 > 53-58

We evaluated 16 pregnant women with gestational age between 20 and 32 weeks in acute severe hypertension which were randomly allocated to receive either hydralazine or labetalol. Blood pressure and Doppler ultrasound parameters from maternal uterine and fetal middle cerebral and umbilical arteries were assessed during acute severe hypertension and after treatment. A significant reduction in systolic...

article

Ultrasonography in pregnant women with antiphospholipid syndrome using salicylic acid and heparin

Ana Carolina S. Calderon, Aderson T. Berezowski, Alessandra Cristina Marcolin, Wellington P. Martins, more

Archives of Gynecology and Obstetrics > 2011 > 284 > 1 > 79-84

Purpose The objective of the present study was to evaluate fetal biometry, Doppler values, and perinatal outcomes in pregnant women with antiphospholipid syndrome treated with acetylsalicylic acid and heparin. Study design Twenty-five pregnant women with antiphospholipid syndrome using 100 mg/day acetylsalicylic acid and 5,000 IU heparin every 12 h were evaluated in this prospective observational...

article

Interethnic differences in ADMA concentrations and negative association with nitric oxide formation in preeclampsia

Valeria C. Sandrim, Ana C.T. Palei, Ingrid F. Metzger, Ricardo C. Cavalli, more

Clinica Chimica Acta > 2010 > 411 > 19-20 > 1457-1460

Recent studies have suggested that impaired nitric oxide (NO) formation in preeclampsia may result from increased concentrations of an endogenous NO synthase inhibitor, the asymmetric dimethylarginine (ADMA). However, no previous study has examined whether a negative association exists between ADMA and nitrite concentrations in preeclampsia. Moreover, no previous study has compared ADMA and nitrite...

article

Increased circulating cell-free hemoglobin levels reduce nitric oxide bioavailability in preeclampsia

Valeria C. Sandrim, Marcelo F. Montenegro, Ana C.T. Palei, Ingrid F. Metzger, more

Free Radical Biology and Medicine > 2010 > 49 > 3 > 493-500

Contrasting with increased nitric oxide (NO) formation during healthy pregnancy, reduced NO bioavailability plays a role in preeclampsia. However, no study has examined whether increased NO consumption by enhanced circulating levels of cell-free hemoglobin plays a role in preeclampsia. We studied 82 pregnant women (38 healthy pregnant and 44 with preeclampsia). To assess NO bioavailability, we measured...

article

Matrix metalloproteinase (MMP)-9 genotypes and haplotypes in preeclampsia and gestational hypertension

Ana C.T. Palei, Valeria C. Sandrim, Geraldo Duarte, Ricardo C. Cavalli, more

Clinica Chimica Acta > 2010 > 411 > 11-12 > 874-877

Abnormal production of matrix metalloproteinases (MMPs), especially MMP-9, may play a role in hypertensive disorders of pregnancy. These alterations may result from functional genetic polymorphisms in the promoter region of MMP-9 gene, which are known to change MMP-9 expression. We examined whether 2 MMP-9 polymorphisms (C ⁻¹⁵⁶² T and (CA)n) and haplotypes are associated with preeclampsia...

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Keywords

PREECLAMPSIA (11)
GESTATIONAL HYPERTENSION (4)
NITRIC OXIDE (4)
ADIPONECTIN (2)
ADMA (2)
HAPLOTYPE (2)
NITRITE (2)
POLYMORPHISM (2)
PREGNANCY (2)
ULTRASONOGRAPHY (2)
ANTERIOR CINGULATE GYRUS (1)
ANTIPHOSPHOLIPID SYNDROME (1)
CYCLIC GMP (1)
DOPPLER (1)
ETHNICITY (1)
GENETIC POLYMORPHISM (1)
GENOTYPE (1)
HEPARIN (1)
HYDRALAZINE (1)
HYPERTENSION (1)
LABETALOL (1)
LEPTIN (1)
MAGNETIC RESONANCE SPECTROSCOPY, DORSOLATERAL PREFRONTAL CORTEX (1)
MAJOR DEPRESSIVE DISORDER (1)
MATRIX METALLOPROTEINASE (MMP)-2 (1)
MATRIX METALLOPROTEINASES (1)
METALLOPROTEINASE (MMP)-2 AND (MMP)-9 (1)
METALLOPROTEINASES (1)
MMP-9 (1)
NATRIURETIC PEPTIDES (1)
NO (1)
POSTPARTUM DEPRESSION (1)
PREGNANCY-INDUCED (1)
SALICYLIC ACID (1)
SFLT-1 (1)
SR (1)
TIMPS (1)
TISSUE INHIBITOR OF METALLOPROTEINASE (TIMP)-1 AND (TIMP)-2 (1)
TRACE ELEMENTS (1)
VEGF (1)
VITAMIN D RECEPTOR (1)
ZN (1)
more

Data set

Elsevier (18)
Springer (3)
Wiley (1)

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Search results for: Ricardo C. Cavalli

Glutamatergic and neural dysfunction in postpartum depression using magnetic resonance spectroscopy

Positive correlations between circulating adiponectin and MMP2 in preeclampsia pregnant

Correlations among antiangiogenic factors and trace elements in hypertensive disorders of pregnancy

Influence of type 2 diabetes mellitus on the pharmacokinetics and placental transfer of nifedipine in hypertensive pregnancy women

Risk factors influencing the development of hypertension in pregnancy in a convenience cohort

Influence of a physiotherapy protocol in maternal and fetal hemodynamics in pregnant women with preeclampsia

Assessment of quality of life of women with preeclampsia compared with healthy pregnant women

Relationship of uterine artery flow in the second trimester of pregnancy with the neurodevelopment of children in the second year of life – A cohort study

Assessment of concentrations of sFlt-1 and PlGF as predictors of preeclampsia

Antihypertensive therapy in preeclampsia is not modulated by VEGF polymorphisms

Relationship between adiponectin and nitrite in healthy and preeclampsia pregnancies

Effects of Matrix Metalloproteinase (MMP)‐2 Polymorphisms on Responsiveness to Antihypertensive Therapy of Women with Hypertensive Disorders of Pregnancy

Association between matrix metalloproteinase (MMP)-2 polymorphisms and MMP-2 levels in hypertensive disorders of pregnancy

Vitamin D receptor polymorphisms in hypertensive disorders of pregnancy

Alterations in cyclic GMP levels in preeclampsia may reflect increased B-type natriuretic peptide levels and not impaired nitric oxide activity

Changes in Fetal and Maternal Doppler Parameters Observed During Acute Severe Hypertension Treatment with Hydralazine or Labetalol: A Randomized Controlled Trial

Ultrasonography in pregnant women with antiphospholipid syndrome using salicylic acid and heparin

Interethnic differences in ADMA concentrations and negative association with nitric oxide formation in preeclampsia

Increased circulating cell-free hemoglobin levels reduce nitric oxide bioavailability in preeclampsia

Matrix metalloproteinase (MMP)-9 genotypes and haplotypes in preeclampsia and gestational hypertension

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