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The effects of α-MSH on ovarian progesterone (P) and estradiol (E 2 ) release were investigated. To this purpose, different doses of α-MSH were administered to prepubertal ovaries incubated under the following conditions: ten 5 min-pulses of perfusion medium (PM) plus LH at 160 ng/ml each one followed by a 25-min period of PM. The medium of the treated group contained α-MSH (0.1, 1, 5, or...