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Deep brain stimulation (DBS) is an established therapy to treat motor symptoms in movement disorders such as Parkinson’s disease (PD). However, its mechanisms are still poorly understood. Oscillatory activity,on the other hand, plays a crucial role in the pathophysiology of PD. Investigating the effect of DBS on oscillatory activity can help to clarify the neurophysiological mechanisms of DBS. In...
Walking abilities are severely affected in patients suffering from Freezing of Gait (FOG), a common phenomenon in advanced Parkinson’s disease (PD). Despite the high occurrence of the symptom in the progression of the disease, little is known about the underlying mechanisms. Remarkably, it was recently reported that patients with FOG are still able to ride a bike (Snijders et al., 2011; Snijders et...