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We wish to report the detection of dimethyl sulfone (methylsulfonylmethane, C 2 H 6 O 2 S) in the brain of a normal 62-year-old male using in vivo proton magnetic resonance spectroscopy. The presence of this exogenous metabolite resulted from ingestion of a dietary supplement containing dimethyl sulfone. The concentration of this compound in the brain was measured to be 2.4...