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Periampullary adenocarcinomas can be of two histological subtypes, intestinal or pancreatobiliary. The latter is more frequent and aggressive, and characterized by a prominent desmoplastic stroma, which is tightly related to the biology of the cancer, including its poor response to chemotherapy. Whereas miRNAs are known to regulate various cellular processes and interactions between cells, their exact...
Model predictive control (MPC) solves an optimization at every sampling instance to achieve commanded set points and control objectives subject to constraints on control inputs and system states. Such online optimization can incorporate many important factors to enable the control of systems subject to faults, changing dynamics, changing control objectives, failed control inputs and large disturbances...
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