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The addition of alpha-2 agonists clonidine and dexmedetomidine to intra-articular (IA) infiltration of local anaesthetics (LA) may prolong the duration of action of analgesia following arthroscopic knee surgery. The objective of this systematic review and meta-analysis was to evaluate the analgesic effect of addition of alpha-2 agonists to LA when used for day case arthroscopic knee surgery.PubMed,...