Search results for: Peter F. Kokkinos

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Impact of Cardiorespiratory Fitness on Mortality in Black Male Veterans With Resistant Systemic Hypertension

Puneet Narayan, Michael Doumas, Anubhav Kumar, Charles J. Faselis, more

The American Journal of Cardiology > 2017 > 120 > 9 > 1568-1571

Patients with resistant systemic hypertension have poorer outcomes than nonresistant hypertensives. The purpose of this study was to evaluate the association between cardiorespiratory fitness and all-cause mortality in black male Veterans with resistant systemic hypertension. Patients were identified from a cohort undergoing exercise tolerance test at the department of Veterans Affairs Medical Center...

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Impact of Changes in Cardiorespiratory Fitness on Hypertension, Dyslipidemia and Survival: An Overview of the Epidemiological Evidence

Xuemei Sui, Mark A. Sarzynski, Duck-chul Lee, Peter F. Kokkinos

Progress in Cardiovascular Diseases > 2017 > 60 > 1 > 56-66

Over the last fifty years, cardiorespiratory fitness (CRF) has been firmly established as an important risk factor for cardiovascular disease (CVD) and all-cause mortality. Mounting evidence supports a strong and inverse association between baseline CRF and the risk of developing hypertension (HTN) and dyslipidemia. Accumulating evidence also suggests that improving or maintaining a certain level...

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The Interaction of Cardiorespiratory Fitness With Obesity and the Obesity Paradox in Cardiovascular Disease

Ahmet Afşin Oktay, Carl J. Lavie, Peter F. Kokkinos, Parham Parto, more

Progress in Cardiovascular Diseases > 2017 > 60 > 1 > 30-44

Overweight and obesity are well-established risk factors for most cardiovascular diseases (CVD), including coronary heart disease (CHD), heart failure (HF), and atrial fibrillation. Despite the strong link between excess adiposity and risk of CVD, growing evidence has demonstrated an obesity paradox in patients with CVD. This phenomenon is characterized by a better prognosis in overweight and mildly...

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Longitudinal Patterns of Cardiorespiratory Fitness Predict the Development of Hypertension Among Men and Women

Xuemei Sui, Mark A. Sarzynski, Duck-chul Lee, Carl J. Lavie, more

The American Journal of Medicine > 2017 > 130 > 4 > 469-476.e2

Most of the existing literature has linked a baseline cardiorespiratory fitness or change between baseline and one follow-up measurement of cardiorespiratory fitness to hypertension. The purpose of the study is to assess the association between longitudinal patterns of cardiorespiratory fitness changes with time and incident hypertension in adult men and women.Participants were aged 20 to 82 years,...

article

Cardiorespiratory Fitness and Incidence of Major Adverse Cardiovascular Events in US Veterans: A Cohort Study

Peter F. Kokkinos, Charles Faselis, Jonathan Myers, Puneet Narayan, more

Mayo Clinic Proceedings > 2017 > 92 > 1 > 39-48

To assess the association between exercise capacity and the risk of major adverse cardiovascular events (MACEs).A symptom-limited exercise tolerance test was performed to assess exercise capacity in 20,590 US veterans (12,975 blacks and 7615 whites; mean ± SD age, 58.2±11.0 years) from the Veterans Affairs medical centers in Washington, District of Columbia, and Palo Alto, California. None had a history...

article

The Impact of Cardiorespiratory Fitness Levels on the Risk of Developing Atherogenic Dyslipidemia

Charity B. Breneman, Kristen Polinski, Mark A. Sarzynski, Carl J. Lavie, more

The American Journal of Medicine > 2016 > 129 > 10 > 1060-1066

Low cardiorespiratory fitness has been established as a risk factor for cardiovascular-related morbidity. However, research about the impact of fitness on lipid abnormalities, including atherogenic dyslipidemia, has produced mixed results. The purpose of this investigation is to examine the influence of baseline fitness and changes in fitness on the development of atherogenic dyslipidemia.All participants...

chapter

Exercise Therapy for Lower Extremity Arterial Disease

Peter F. Kokkinos

Clinical Hypertension and Vascular Diseases > Lower Extremity Arterial Disease > 243-256

Atherosclerosis is a progressive, generalized disease affecting the entire arterial system. The development of atherosclerotic lesions in the large arteries of the lower extremities eventually leads to significant stenosis. Consequently, blood flow distal to the lesions is significantly impaired. The condition is referred to as lower extremity arterial disease (LEAD).

article

Statin therapy, fitness status and risk of type 2 diabetes in hypertensive patients

Puneet Narayan, Charles C. Faselis, Andreas Pittaras, Michael Doumas, more

Journal of the American Society of Hypertension > 2016 > 10 > 4(S) > e32

article

The Effect of Cardiorespiratory Fitness on Age-Related Lipids and Lipoproteins

Yong-Moon Mark Park, Xuemei Sui, Junxiu Liu, Haiming Zhou, more

Journal of the American College of Cardiology > 2015 > 65 > 19 > 2091-2100

Evidence on the effect of cardiorespiratory fitness (CRF) on age-related longitudinal changes of lipids and lipoproteins is scarce.This study sought to assess the longitudinal aging trajectory of lipids and lipoproteins for the life course in adults and to determine whether CRF modifies the age-associated trajectory of lipids and lipoproteins.Data came from 11,418 men, 20 to 90 years of age, without...

article

Interactive effects of fitness and statin treatment on mortality risk in veterans with dyslipidaemia: a cohort study

Peter F Kokkinos, Charles Faselis, Jonathan Myers, Demosthenes Panagiotakos, more

The Lancet > 2013 > 381 > 9864 > 394-399

Statins are commonly prescribed for management of dyslipidaemia and cardiovascular disease. Increased fitness is also associated with low mortality and is recommended as an essential part of promoting health. However, little information exists about the combined effects of fitness and statin treatment on all-cause mortality. We assessed the combined effects of statin treatment and fitness on all-cause...

article

Obesity Paradox and Cardiorespiratory Fitness in 12,417 Male Veterans Aged 40 to 70 Years

Paul A. McAuley, Peter F. Kokkinos, Ricardo B. Oliveira, Brian T. Emerson, more

Mayo Clinic Proceedings > 2010 > 85 > 2 > 115-121

To evaluate the influence of cardiorespiratory fitness (fitness) on the obesity paradox in middle-aged men with known or suspected coronary artery disease. This study consists of 12,417 men aged 40 to 70 years (44% African American) who were referred for exercise testing at the Veterans Affairs Medical Centers in Washington, DC, or Palo Alto, CA (between January 1, 1983, and June 30, 2007). Fitness...

article

Reply

Peter F. Kokkinos, Steven Singh, Puneet Narayan

Journal of the American College of Cardiology > 2006 > 48 > 6 > 1285

article

Abnormal exercise blood pressure predicts left ventricular mass in pre-hypertensive, middle-aged men and women

Andreas E. Pittaras, Peter F. Kokkinos, Athanasios J. Manolis, Puneet Narayan, more

American Journal of Hypertension > 2005 > 18 > 5 Supplement > A190-A191

article

Nondippers have higher incidence of abnormal exercise blood pressure response left ventricular hypertrophy and diastolic dysfunction in pre-hypertensive and hypertensive men

Andreas E. Pittaras, Peter F. Kokkinos, Athanasios J. Manolis, Puneet Narayan, more

American Journal of Hypertension > 2005 > 18 > 5 Supplement > A43

article

Left ventricular hypertrophy in hypertensive African-americans with coronary artery disease increases the 10 year mortality risk

Andreas E. Pittaras, Peter F. Kokkinos, Athanasios J. Manolis, Puneet Narayan, more

American Journal of Hypertension > 2004 > 17 > 5 Supplement > S27

OR-62Key Words: Left Ventricular Hypertrophy (LVH), African-Americans, Coronary Artery Disease

article

Lower left ventricular mass, 24-hr blood pressure and exercise blood pressure in fit vs unfit middle-aged men and women

Andreas E. Pittaras, Peter F. Kokkinos, Athanasios J. Manolis, Puneet Narayan, more

American Journal of Hypertension > 2003 > 16 > 5 Supplement > A76-A77

article

Arterial compliance improves in diabetic, normotensive patients after ACE-inhibition therapy

Stiliani Iraklianou, Athanasios J. Manolis, Ioannis Volonakis, Andreas E. Pittaras, more

American Journal of Hypertension > 2002 > 15 > 4 Supplement 1 > A73

article

Chronic heart failure and exercise

Peter F. Kokkinos, Wassim Choucair, Page Graves, Vasilios Papademetriou, more

American Heart Journal > 2000 > 140 > 1 > 21-28

article

Effects of Moderate Intensity Exercise on Serum Lipids in African-American Men With Severe Systemic Hypertension

Peter F. Kokkinos, Puneet Narayan, John Colleran, Ross D. Fletcher, more

The American Journal of Cardiology > 1998 > 81 > 6 > 732-735

The prevalence of systemic hypertension and its cardiovascular consequences is higher in African-Americans than in whites. Low to moderate intensity aerobic exercise lowers blood pressure (BP) in African-american patients with severe hypertension. It is not known whether such exercise can improve lipid metabolism in these patients. Thirty-six African-American men with established essential hypertension,...

article

Value of the Electrocardiogram in Determining Cardiac Events and Mortality in Myotonic Dystrophy

John A. Colleran, Rollin J. Hawley, Ellen E. Pinnow, Peter F. Kokkinos, more

The American Journal of Cardiology > 1997 > 80 > 11 > 1494-1497

In summary, the electrocardiogram remains a useful tool for evaluating and following patients with myotonic dystrophy. Meticulous attention and frequent follow-up should be considered in patients with a PR interval ≥240 ms and in those aged >40 years.

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INFONA - science communication portal

Search results for: Peter F. Kokkinos

Impact of Cardiorespiratory Fitness on Mortality in Black Male Veterans With Resistant Systemic Hypertension

Impact of Changes in Cardiorespiratory Fitness on Hypertension, Dyslipidemia and Survival: An Overview of the Epidemiological Evidence

The Interaction of Cardiorespiratory Fitness With Obesity and the Obesity Paradox in Cardiovascular Disease

Longitudinal Patterns of Cardiorespiratory Fitness Predict the Development of Hypertension Among Men and Women

Cardiorespiratory Fitness and Incidence of Major Adverse Cardiovascular Events in US Veterans: A Cohort Study

The Impact of Cardiorespiratory Fitness Levels on the Risk of Developing Atherogenic Dyslipidemia

Exercise Therapy for Lower Extremity Arterial Disease

Statin therapy, fitness status and risk of type 2 diabetes in hypertensive patients

The Effect of Cardiorespiratory Fitness on Age-Related Lipids and Lipoproteins

Interactive effects of fitness and statin treatment on mortality risk in veterans with dyslipidaemia: a cohort study

Obesity Paradox and Cardiorespiratory Fitness in 12,417 Male Veterans Aged 40 to 70 Years

Reply

Abnormal exercise blood pressure predicts left ventricular mass in pre-hypertensive, middle-aged men and women

Nondippers have higher incidence of abnormal exercise blood pressure response left ventricular hypertrophy and diastolic dysfunction in pre-hypertensive and hypertensive men

Left ventricular hypertrophy in hypertensive African-americans with coronary artery disease increases the 10 year mortality risk

Lower left ventricular mass, 24-hr blood pressure and exercise blood pressure in fit vs unfit middle-aged men and women

Arterial compliance improves in diabetic, normotensive patients after ACE-inhibition therapy

Chronic heart failure and exercise

Effects of Moderate Intensity Exercise on Serum Lipids in African-American Men With Severe Systemic Hypertension

Value of the Electrocardiogram in Determining Cardiac Events and Mortality in Myotonic Dystrophy

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