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CRISPR/Cas9 has been emerging as a main player in genome editing field since its advent. However, CRISPR/Cas9‐induced precise gene editing remains challenging since it requires no scar left after editing. Among the few reports regarding two‐step ‘pop in & out’ technologies for precise gene editing, the combination of CRISPR/Cas9 with Cre/LoxP demonstrates a higher efficiency, but leaves behind...
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