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In Down's syndrome the extra chromosome in no 21 yields increased activity of superoxide dismutase (SOD) in the erythrocytes. In a study of 15 patients with Down's syndrome 6 patients were treated with sodium selenite. Untreated patients presented significant lower concentration of zinc and increased concentration of copper and titanium in the erythrocytes, increased copper concentration in the neutrophil...
Monitoring changes of elements when supplementing studies are often restricted to one compartment and few parametrs at a time. Often the increase of the supplemented element is analysed in blood plasma or the erythrocytes. Using this technique some information may be lost as other elements not analysed may be important and the conclusion of the study may be incomplete. The access to multielemental...