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A 60-year-old female without coronary risk factors was admitted to the hospital with ST-elevation acute coronary syndrome (ACS). She had previously suffered breast cancer and received radical mastectomy followed by chemotherapy and radiation. Emergent coronary angiography showed an occlusion of the proximal left anterior descending coronary artery (LAD) and coronary angioplasty was performed. Coronary...
Independent predictors of the severity of coronary atherosclerosis are ill defined. We sought to determine the predictors and examine the association of impaired glucose tolerance with stenosis severity. Four hundred thirty-seven patients were studied who underwent coronary angiography for suspected coronary artery disease. Serum concentrations of total cholesterol (TC), triglyceride (TG), high-density...
The endothelium-dependent vasodilation of the epicardial coronary artery in patients with hypercholesterolemia is impaired and restored with the cholesterol lowering drugs. To examine whether acute cholesterol lowering with LDL-apheresis (LDL-aph) improves endothelial function of the epicardial coronary artery, we studied in 10 patients (< 25% focal stenosis) the coronary diameter response with...
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