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Increasing evidence suggests that noise-induced hearing loss may be reduced or prevented with antioxidant therapy. Biochemical markers of reactive oxygen species (ROS)-induced damage can help elucidate possible treatment timing constraints. This study examined the time course of ROS damage following a 2-h, broad-band noise exposure resulting in permanent threshold shift in 35 Long-Evans rats. Cochlea,...
Offset auditory brainstem response (ABR) traditionally has been thought to be an artifactual response elicited by stimulus acoustic ringing. Additionally, offset ABR's sensitivity to stimulus rise-fall time has been associated with concurrent changes in acoustic ringing. The present study tested the validity of offset ABR by recording the response in 40 young, normal-hearing adults using tone burst...
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