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AIM We examined the effect of EGF on hepatic blood flow, serum ALT level and hepatic tissue PGE2 in animal model of acute hepatic failure. METHOD)EGF(20 μg/kg.Bw.) or saline was administrated iv, to male SD rats weighing about 250g. After 30minutes,D-galactosamine (D-gal) was injected at 1g/k g.B w. ip.Hepatic tissue blood flow(HTBF) and hepatic tissue PGE2 were measured by semiconductor laser...