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A great number of milk-derived peptides have been shown to exhibit angiotensin converting enzyme (ACE) inhibitory properties and thus potential utility in the regulation of blood pressure. The present work aimed to investigate the effects of 2 milk trypsin hydrolysates from α S1 - and α S2 -casein (CH1 and CH2, respectively) on ACE activity evaluated in human umbilical vein endothelial...
Bovine α S2 -casein was purified by anionic exchange and hydrophobic interaction chromatographies. The purified α S2 -casein was hydrolysed with trypsin; the resulting peptides were identified by amino acids composition and on line reversed-phase high performance liquid chromatography coupled with electrospray mass spectrometry. A study on the kinetics of peptide release...
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