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Autophagy is responsible for the bulk degradation of cytoplasmic contents including organelles through the lysosomal machinery. Neonatal hypoxia–ischemia (HI) causes cell death in the brain by caspase-dependent and independent pathways. Ischemic insults also increase the formation of autophagosomes and activate autophagy. This study assessed the possible sex- and region-specific differences of autophagy...
The aim of this study was to assess the effects of the organoselenium compound, 3′3-ditrifluormethyldiphenyl diselenide [(F 3 CPhSe) 2 ], during the intra-uterine development of Wistar rats. Dams were given repeated doses of 1, 5 or 10mg/kg (F 3 CPhSe) 2 by intragastric route on gestation days 6–15, and cesarean sections were performed on day 20 of pregnancy. The numbers...
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