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In order to meet the global demand for rapid production of pandemic influenza vaccines, we have developed a recombinant fusion vaccine platform in which the globular head of hemagglutinin (HA) antigen is genetically fused to bacterial flagellin (a TLR5 ligand). These flagellin-HA fusion vaccine candidates elicit highly protective immunity against a lethal challenge with 2009 pandemic H1N1 (Liu, et...
A liquid–solid circulating fluidized bed (LSCFB) system consisting of 3.8 cm I.D. and 4 m high riser and 12 cm I.D. and 3.5 m high down-comer was investigated in this study for the continuous polymerization of phenol. Approximately 8.5 kg immobilized particles containing soybean seed hull peroxidase enzymes were applied in the LSCFB system. The continuous enzymatic polymerization was carried out in...
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