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The antiplasmodial activity of plant extracts related to four families was tested on chloroquine sensitive strain 3D7 and chloroquine resistant strain Dd2 of Plasmodium falciparum. The methanolic extract of Harrisonia abyssinica (Simaroubaceae) inhibited Dd2 with IC 50 value of 4.7 μg/ml, while in 3D7, the IC 50 value was 10 μg/ml. Most of the plants from the family Meliaceae showed...