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An implantable 16-channel neural recording front-end system is presented for acute neural recording. This system consists of implantable silicon-based microelectrode arrays, neural-signal amplifiers and a microprocessor. The neural-signal amplifiers, which have been fabricated by a 0.35-μm CMOS process, have a mid-band gain of 66.5 dB, a high cut-off frequency at 9.6 kHz. Each recording channel has...
An implantable 16-channel neural recording front-end system is presented for acute neural recording. This system consists of implantable silicon-based microelectrode arrays, neural amplifiers and a microprocessor. The neural amplifiers, which have been fabricated in 0.35 μm 2P4M CMOS process, have a mid-band gain of 66.5 dB, a high cut-off frequency of 5.7 kHz. Each recording channel has a tunable...
A prototype microsystem is presented for wireless neural recording application. An inductive link was built for transcutaneous wireless power transfer and data transmission. Total 16.5 mW power and 50 bps - 2.5 Kbps command data can be received over 1-5 MHz with a distance of 0-10 mm. The integrated amplifiers were designed with a limited bandwidth for neural signals acquisition. The gain of 60 dB...
Extracellular neural recording requires neural probes having more recording sites as well as limited volumes. With its mechanical characteristic and abundant process method, Silicon is a kind of material fit for producing neural probe. Silicon on insulator (SOI) is adopted in this paper to fabricate neural probes. The uniformity and manufacturability are improved. The fabricating process and testing...
A prototype neuro-stimulus chip for sub-retinal implants in blind patients affected by age-related macular degeneration (AMD) or retinitis pigmentosa (RP) is presented in this paper. This retinal prosthetic chip was designed to replace the degenerated photoreceptor cells, and in order to stimulate directly the remaining healthy layers of retinal neurons. The current stimulus circuits are monolithic...
Based on the McNeal cable model, taking the myelinated nerve fiber with limited length as the research object, three models (FH model, CRRSS model and SE model) were used in this paper to simulate the conduction block phenomena induced by symmetric biphasic electrical currents. The simulation ability of FH, CRRSS and SE models was also evaluated. The nerve conduction can be blocked above 10 kHz in...
Nerve conduction block induced by high frequency biphasic electrical current was simulated using a lumped circuit model of the myelinated axon based on Frankenhaueuser-Huxley (FH) equations. Axons of different diameters (5-20 mum) can be blocked completed when the stimulation frequency is above 10 kHz. At higher frequency a higher stimulation intensity is needed to block nerve conduction. Larger diameter...
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