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Aims/hypothesis Atorvastatin exerts beneficial vascular effects in diabetes, but the underlying mechanisms are yet to be elucidated. The aim of the present study was to determine whether Rac-1 is involved in the effect of atorvastatin on oxidative stress and vascular dysfunction. Materials and methods Using human aortic endothelial cells (HAECs) we evaluated the effect of high glucose levels on...
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