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Background The Runx family proteins, including RUNX3, are tissue-restricted transcription factors and play role in neuronal development and tumorigenesis. RUNX3 has an important role in glioblastoma (GBM) tumorigenesis because of its promoter hypermethylation. Aim We aimed to evaluate the methylation-mediated expression regulation of RUNX3 gene in brain tumors. Patients and methods Cases of...
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