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Many, but not all, previous epidemiological studies indicated a greater risk of hepatocellular cancer (HCC) in women who have used combined oral contraceptives for a long period of time, but no one has analyzed this risk based upon use of different formulations.It was decided to analyze specifically the risk of OC containing cyproterone acetate (CPA) after toxicological experiments in animals found...
Recent years have seen a discussion on which group of patients should be offered chemotherapy for advanced CRC regarding the limited efficacy and high costs of treatment and its' possible side effects on patients' QL. In a randomized phase III trial, 142 patients with advanced CRC were treated with 5-fluorouracil and either interferon α-2b or folinic acid. For the QL self-assessment before and during...
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