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Les bactéries multirésistantes constituent désormais un problème majeur de santé publique. Plusieurs mécanismes sont à la base de cette multirésistance aux antibiotiques. L’inactivation enzymatique reste cependant le mécanisme prépondérant et en particulier la production de bêtalactamases. D’importance notable sont les bêtalactamases à spectre étendu (BLSE) d’Escherichia coli et de Klebsiella pneumoniae...