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Background: The effect of transfusion of small amounts of packed red blood cells (PRBC) on serum chemistry values is not known.Methods: We studied 73 adult patients without evidence of bleeding who received 2-unit PRBC transfusions. In study 1 (n = 39), we examined multiple laboratory values pretransfusion and 15 minutes, 1 hour, 2 hours, and 24 hours posttransfusion. In study 2 (n = 34), we examined...