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Background: Free oxygen radicals have been proposed as important causative agents of aging. We have evaluated age-related changes in antioxidant enzyme activities and lipid peroxidation. Methods: We measured erythrocyte superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx) and plasma malondialdehyde (MDA) levels. One hundred and seventy six healthy subjects were divided into five...
Objectives: An increasing amount of experimental and epidemiological evidence implicates the involvement of oxygen derived radicals in the pathogenesis of cancer development. Oxygen derived radicals are able to cause damage to membranes, mitochondria, and macromolecules including proteins, lipids and DNA. Accumulation of DNA damages has been suggested to contribute to carcinogenesis. It would, therefore,...
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