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Abstract. Objective: First, to evaluate the role of typical intensive care-related conditions like sepsis, prolonged ventilation, drug effects and metabolic disorders in the pathogenesis of critical illness polyneuropathy (CIP); second, to investigate the possible significance of patient serum neurotoxicity assessed by an in vitro cytotoxicity assay with respect to CIP development. Design: Prospective...
Dans la maladie de Fabry, le déficit enzymatique en α-galactosidase A mène à l’accumulation des glycosphingolipides dans les liquides organiques et les tissus tels que les cornées, les vaisseaux sanguins, les reins et les structures des systèmes nerveux central et périphérique.De nombreux patients manifestent un dysfonctionnement cardiovasculaire et cérébrovasculaire. Ce dernier est particulièrement...
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