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Cognitive deficits have been reported during the early stages of bipolar disorder; however, the role of medication on such deficits remains unclear. The aim of this study was to compare the effects of lithium and quetiapine monotherapy on cognitive performance in people following first episode mania.The design was a single-blind, randomised controlled trial on a cohort of 61 participants following...
Despite cognition being normal or even superior tocontrols prior to a first episode of mania, there is a decline in cognitivecapacity that is arguably steepest in the interval after a first episode ofmania. What is unclear, is the extent to which this can be prevented and whichagents might be most useful for doing so. This study reports the outcomes of a single-blind, randomised control trial of...
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