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The system architecture presented in this paper is designed for helping an aged person to live longer independently in their own home by detecting unusual and potentially hazardous behaviours. The system consists of two major components. The first component is the tracking part which is responsible for monitoring the movements of the person within the home, while the second part is a learning agent...
Objective: Venodilatation is a feature of endotoxaemia and sepsis. We have tested directly the hypothesis that three cytokines (IL-1β, TNFα and IL-6) generated during endotoxaemia affect venous tone in humans in vivo by increasing NO generation and explored whether the NO comes from the iNOS or eNOS isoform. Design and intervention: Cytokines were given into a superficial vein in very low doses...
Background: There is an association between infection, inflammation and acute cardiovascular events. In an attempt to explore the mechanism of this association we have developed a model to examine the effects on endothelial function of a brief exposure to endotoxin. Methods and results: Endotoxin was instilled into isolated superficial hand veins of healthy volunteers. The vein was isolated by...
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