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Several responses of synchronized populations of HeLa S3 cells were measured after irradiation with 220 kev x-rays at selected times during the division cycle. (1) Survival (colony-forming ability) is maximal when cells are irradiated in the early post-mitotic (G 1 ) and the pre-mitotic (G 2 ) phases of the cycle, and minimal in the mitotic (M) and late G 1 or early DNA synthetic...