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Objective
This study was undertaken to develop a novel pathway linking genetic data with routinely collected data for people with epilepsy, and to analyze the influence of rare, deleterious genetic variants on epilepsy outcomes.
Methods
We linked whole‐exome sequencing (WES) data with routinely collected primary and secondary care data and natural language processing (NLP)‐derived seizure frequency...
Objective
This study was undertaken to determine whether epilepsy and antiepileptic drugs (including enzyme‐inducing and non‐enzyme‐inducing drugs) are associated with major cardiovascular events using population‐level, routinely collected data.
Methods
Using anonymized, routinely collected, health care data in Wales, UK, we performed a retrospective matched cohort study (2003–2017) of adults with...
Anonymised, routinely-collected healthcare data is increasingly being used for epilepsy research. We validated algorithms using general practitioner (GP) primary healthcare records to identify people with epilepsy from anonymised healthcare data within the Secure Anonymised Information Linkage (SAIL) databank in Wales, UK.A reference population of 150 people with definite epilepsy and 150 people without...
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