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The coral metamorphosis-enhancing compound luminaolide was isolated from the crustose coralline algae (CCA) Hydrolithon reinboldii, and was shown to 34-membered macrodiolide skeleton. The relative configuration of luminaolide was established based on 1 H– 1 H coupling constants, steric information from ROESY and a J-based configuration analysis using long-range 1 H– 13...
Lyngbyacyclamides A (1) and B (2), novel cyclic peptides, were isolated from marine cyanobacteria Lyngbya sp. collected in Okinawa, Japan. Their structures were determined by spectroscopic analyses and degradation studies. They moderately inhibited the growth of B16 mouse melanoma cells.
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