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The venom from the marine snail Conus pennaceus inhibits the binding of [ 3 H]neuropeptide Y to calf brain membranes (Czerwiec et al., 1996a) and, in the present study, also to rat forebrain membranes. These membranes contain about 80% Y 1 - and 20% Y 2 -receptors. The inhibition by the venom was concentration-dependent with an IC 50 value of 3.4 μg ml -...