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Patients with ventricular assist devices still suffer from high rates of adverse events. Since many of these complications are linked to the flow field within the pump, optimization of the device geometry is essential. To investigate design aspects that influence the flow field, we developed a centrifugal blood pump using industrial guidelines. We then systematically varied selected design parameters...
Single ventricle congenital heart defects, which are characterized by cyanotic mixing between the oxygenated and de-oxygenated blood, afflict 2 per every 1000 live births. These defects are surgically treated by connecting the superior and inferior vena cava to the pulmonary arteries. However, such a configuration (also known as the total cavopulmonary connection), results in high energy losses and...
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