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Pheromone responses are highly context dependent. For example, the C. elegans pheromone ascaroside C9 (ascr#3) is repulsive to wild-type hermaphrodites, attractive to wild-type males, and usually neutral to “social” hermaphrodites with reduced activity of the npr-1 neuropeptide receptor gene. We show here that these distinct behavioral responses arise from overlapping push-pull circuits driven by...
Most heritable behavioral traits have a complex genetic basis, but few multigenic traits are understood at a molecular level. Here we show that the C. elegans strains N2 and CB4856 have opposite behavioral responses to simultaneous changes in environmental O 2 and CO 2 . We identify two quantitative trait loci (QTL) that affect this trait and map each QTL to a single-gene polymorphism...
Due to its unique optical properties, nanostructured silicon is a promising material for optoelectronic applications, solar energy conversion and chemical sensors. This paper demonstrates the incorporation of organic-capped silicon nanoparticles into the hydrophobic interior of phospholipid vesicle bilayers, and uses photoluminescence quenching to determine the accessibility of membrane-embedded nanoparticles...
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