Search results for: Cristina Carvalho

Items from 1 to 20 out of 90 results

article

White matter hyperintensity burden predicts cognitive but not motor decline in Parkinson's disease: results from the Ontario Neurodegenerative Diseases Research Initiative

Daniela Cristina Carvalho de Abreu, Frederico Pieruccini‐Faria, Yanina Sarquis‐Adamson, Alanna Black, more

European Journal of Neurology > 30 > 4 > 920 - 933

Background and purpose The pathophysiology of Parkinson's disease (PD) negatively affects brain network connectivity, and in the presence of brain white matter hyperintensities (WMHs) cognitive and motor impairments seem to be aggravated. However, the role of WMHs in predicting accelerating symptom worsening remains controversial. The objective was to investigate whether location and segmental brain...

article

Professional Nursing Communication Competence: Theoretical procedures for instrument development and pilot test

Samuel Freitas Soares, Elaine Cristina Carvalho Moura, Violeta Lopez, Aida Maris Peres

Journal of Nursing Management > 29 > 6 > 1496 - 1507

Aims To describe the theoretical procedures for the development of the Professional Nursing Communication Competence instrument, determine the content validity and describe the pilot test application. Background Measuring instruments must be developed in accordance with the context and communication process by adopting theoretical procedures based on competence structures to support quality patient‐centred...

article

Revisiting cell and gene therapies in Huntington’s disease

Margarida Beatriz, Carla Lopes, Ana Cláudia S. Ribeiro, Ana Cristina Carvalho Rego

Journal of Neuroscience Research > 99 > 7 > 1744 - 1762

Neurodegenerative movement disorders, such as Huntington's disease (HD), share a progressive and relentless course with increasing motor disability, linked with neuropsychiatric impairment. These diseases exhibit diverse pathophysiological processes and are a topic of intense experimental and clinical research due to the lack of therapeutic options. Restorative therapies are promising approaches with...

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Exploring the causes of the high incidence of delayed graft function after kidney transplantation in Brazil: a multicenter study

Tainá Veras Sandes‐Freitas, Marilda Mazzali, Roberto Ceratti Manfro, Luis Gustavo Modelli Andrade, more

Transplant International > 34 > 6 > 1093 - 1104

This retrospective multicenter (n = 18) cohort study evaluated the incidence, risk factors, and the impact of delayed graft function (DGF) on 1‐year kidney transplant (KT) outcomes. Of 3992 deceased donor KT performed in 2014–2015, the incidence of DGF was 54%, ranging from 29.9% to 87.7% among centers. Risk factors (_{lower‐bound‐95%CI} OR _{upper‐bound‐95%CI}) were male gender (_1.0661.249_1.463), diabetic...

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Relationship between the implementation of primary nursing model and the reduction of missed nursing care

Elaine Cristina Carvalho Moura, Magno Batista Lima, Aida Maris Peres, Violeta Lopez, more

Journal of Nursing Management > 28 > 8 > 2103 - 2112

Aims To evaluate and predict the relationship between the implementation of the primary nursing model and the reduction of missed nursing care. Background Primary nursing can provide hospital leaders and nursing staff with guidance in implementing safe, patient‐centred care, with responsibility and accountability during the nursing process. The implementation can be measured in terms of missed...

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Identification of Needs of Older Adults With Intellectual Disabilities

Cristina P. Albuquerque, Ana Cristina Carvalho

Journal of Policy and Practice in Intellectual Disabilities > 17 > 2 > 123 - 131

Information regarding individual needs of older adults with intellectual disabilities (IDs) is scarce although it is very important both from a person‐centered planning perspective and from a proactive service system perspective. This study has three main aims: (1) to identify and describe staff perceptions of the needs of a large group of adults aged 45 or over with IDs; (2) to analyze the perceived...

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Determination of antimicrobial susceptibility and biofilm production in Staphylococcus aureus isolated from white coats of health university students

Isabela Rotta Batista, Amanda Caroline Lima Prates, Bruna de Souza Santos, Josimara Cristina Carvalho Araújo, more

Annals of Clinical Microbiology and Antimicrobials > 2019 > 18 > 1 > 1-7

This study aimed at detecting Staphylococcus aureus from white coats of college students and characterizing antimicrobial susceptibility and biofilm production. Bacterial samples (n = 300) were obtained from white coats of 100 college students from August 2015 to March 2017 S. aureus was isolated and it´s resistance profile was assessed by antimicrobial disk-diffusion technique, screening for methicillin-resistant...

article

Distal renal tubular acidosis: genetic causes and management

Sílvia Bouissou Morais Soares, Luiz Alberto Wanderley Menezes Silva, Flávia Cristina Carvalho Mrad, Ana Cristina Simões e Silva

World Journal of Pediatrics > 2019 > 15 > 5 > 422-431

Background Distal renal tubular acidosis (dRTA) is a kidney tubulopathy that causes a state of normal anion gap metabolic acidosis due to impairment of urine acidification. This review aims to summarize the etiology, pathophysiology, clinical findings, diagnosis and therapeutic approach of dRTA, with emphasis on genetic causes of dRTA. Data sources Literature reviews and original research articles...

article

Interventions to obstructive long-term central venous catheter in cancer patients: a meta-analysis

Ana Cristina Carvalho Costa, Jéssica Marques Ribeiro, Christiane Inocêncio Vasques, Graziela De Luca Canto, more

Supportive Care in Cancer > 2019 > 27 > 2 > 407-421

Purpose The aim of this systematic review was to identify the interventions used to treat obstructive events, whether thrombotic or non-thrombotic, in long-term central venous catheters (LT-CVC) in cancer patients. Methods This review included clinical trials and observational studies reporting the drugs used to treat obstructive catheter events in cancer patients. The authors developed specific...

article

Contribution of hip abductor–adductor muscles on static and dynamic balance of community-dwelling older adults

Jaqueline Mello Porto, Renato Campos Freire Júnior, Larissa Bocarde, Júlia Adorno Fernandes, more

Aging Clinical and Experimental Research > 2019 > 31 > 5 > 621-627

Background The previous studies have investigated causes of and risk factors for falls and impairment of functional capability in older adults. However, the biomechanical factors involved in functional performance and postural control, and the contribution of hip muscles, are still unknown. Aims The aim of the present study was to verify the association between the muscle function of hip abductors...

article

Evaluation of Portuguese limestones’ susceptibility to salt mist through laboratory testing

Cristina Carvalho, Zenaide Silva, Joaquim Simão

Environmental Earth Sciences > 2018 > 77 > 13 > 1-15

The salt mist present in the coastal shoreline constitutes an important weathering agent of the building materials applied in these regions. Portugal has an extensive coastline, which has a high population density. It holds a long tradition in the use of stone as a building material, due to the abundance of this natural resource, but also because of its durability and beauty. Considering the main...

article

Microplastics cause neurotoxicity, oxidative damage and energy-related changes and interact with the bioaccumulation of mercury in the European seabass, Dicentrarchus labrax (Linnaeus, 1758)

Luís Gabriel Antão Barboza, Luís Russo Vieira, Vasco Branco, Neusa Figueiredo, more

Aquatic Toxicology > 2018 > 195 > C > 49-57

Microplastics pollution is a global paradigm that raises concern in relation to environmental and human health. This study investigated toxic effects of microplastics and mercury in the European seabass (Dicentrarchus labrax), a marine fish widely used as food for humans. A short-term (96 h) laboratory bioassay was done by exposing juvenile fish to microplastics (0.26 and 0.69 mg/L), mercury (0.010...

article

Growth and metabolic parameters of common snook juveniles raised in freshwater with different water hardness

Bruna T. Michelotti, Gabriel Passini, Cristina Carvalho, Josêania Salbego, more

Aquaculture > 2018 > 482 > C > 31-35

The adaptation of common snook Centropomus undecimalis to low salinities and freshwater has being widely studied, but the definition of the best water hardness levels may facilitate the adaptation and growth of this species in freshwater. Consequently, the aim of this study was to evaluate survival, growth and metabolic parameters (blood glucose and osmolality and lactate in plasma and tissues) of...

article

Exercise on balance and function for knee osteoarthritis: A randomized controlled trial

Roberta de Matos Brunelli Braghin, Elisa Cavalheiro Libardi, Carina Junqueira, Marcello Henrique Nogueira – Barbosa, more

Journal of Bodywork and Movement Therapies > 2018 > 22 > 1 > 76-82

To assess balance and function of symptomatic and asymptomatic subjects with knee osteoarthritis (OA) and investigate the influence of physical exercise.Subjects were divided into three groups: Group 1 (n = 15), symptomatic knee OA; Group 2 (n = 11), asymptomatic knee OA; and Group 3 (n = 16), knee OA and no intervention. History of falls, the WOMAC questionnaire, balance and functionality were assessed...

article

Completely illiterate adults can learn to decode in 3 months

Régine Kolinsky, Isabel Leite, Cristina Carvalho, Ana Franco, more

Reading and Writing > 2018 > 31 > 3 > 649-677

The purpose of this case series was to explore whether adults who did not have the opportunity to acquire reading skills during childhood are able to do so rapidly if trained with an adequate literacy program. After 14 weeks of training with a new, optimized, literacy course based on cognitive research, six out of eight participants became able to read words they had never encountered, hence demonstrating...

article

Heat wave and cold spell changes in Iberia for a future climate scenario

Susana Cardoso Pereira, Martinho Marta‐Almeida, Ana Cristina Carvalho, Alfredo Rocha

International Journal of Climatology > 37 > 15 > 5192 - 5205

This study investigates the impacts of climate change scenario on summer heat waves' (HWs) and winter cold spells' (CSs) characteristics for 12 locations over the Iberian Peninsula (IP). These characteristics are duration, recovery factor and intensity. Two future time slices of the chosen scenario are studied, namely, the periods 2046–2065 and 2081–2100 which are compared with a reference climate...

article

Diphenyl diselenide protects against methylmercury‐induced inhibition of thioredoxin reductase and glutathione peroxidase in human neuroblastoma cells: a comparison with ebselen

Daiane F. Meinerz, Vasco Branco, Michael Aschner, Cristina Carvalho, more

Journal of Applied Toxicology > 37 > 9 > 1073 - 1081

Exposure to methylmercury (MeHg), an important environmental toxicant, may lead to serious health risks, damaging various organs and predominantly affecting the brain function. The toxicity of MeHg can be related to the inhibition of important selenoenzymes, such as glutathione peroxidase (GPx) and thioredoxin reductase (TrxR). Experimental studies have shown that selenocompounds play an important...

article

Brain GLP-1/IGF-1 Signaling and Autophagy Mediate Exendin-4 Protection Against Apoptosis in Type 2 Diabetic Rats

Emanuel Candeias, Inês Sebastião, Susana Cardoso, Cristina Carvalho, more

Molecular Neurobiology > 2018 > 55 > 5 > 4030-4050

Type 2 diabetes (T2D) is a modern socioeconomic burden, mostly due to its long-term complications affecting nearly all tissues. One of them is the brain, whose dysfunctional intracellular quality control mechanisms (namely autophagy) may upregulate apoptosis, leading to cognitive dysfunction and Alzheimer disease (AD). Since impaired brain insulin signaling may constitute the crosslink between T2D...

article

The effects of a simultaneous cognitive or motor task on the kinematics of walking in older fallers and non-fallers

Renato Campos Freire Júnior, Jaqueline Mello Porto, Nise Ribeiro Marques, Paola Errera Magnani, more

Human Movement Science > 2017 > 51 > C > 146-152

Human gait has been widely investigated under dual-task conditions because it has been demonstrated to be an important way to uncover differences in gait biomechanics between older fallers and non-fallers. However, exactly how simultaneous tasks affect the kinematics of walking remains unclear. In the present study, gait kinematic properties of older fallers and non-fallers were compared under cognitive...

article

Immediate effects of an anchor system on the stability limit of individuals with chronic dizziness of peripheral vestibular origin

Almir Resende Coelho, Ana Paula do Rego Andre, Júlia Licursi Lambertti Perobelli, Lilian Shizuka Sonobe, more

Brazilian Journal of Otorhinolaryngology > 2017 > 83 > 1 > 3-9

The symptoms associated with chronic peripheral vestibulopathy exert a negative impact on the independence and quality of life of these individuals, and many individuals continue to suffer from these symptoms even after conventional vestibular rehabilitation.To evaluate the acute effect of an anchor system for balance evaluation of patients with chronic dizziness who failed to respond to traditional...

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INFONA - science communication portal

Search results for: Cristina Carvalho

White matter hyperintensity burden predicts cognitive but not motor decline in Parkinson's disease: results from the Ontario Neurodegenerative Diseases Research Initiative

Professional Nursing Communication Competence: Theoretical procedures for instrument development and pilot test

Revisiting cell and gene therapies in Huntington’s disease

Exploring the causes of the high incidence of delayed graft function after kidney transplantation in Brazil: a multicenter study

Relationship between the implementation of primary nursing model and the reduction of missed nursing care

Identification of Needs of Older Adults With Intellectual Disabilities

Determination of antimicrobial susceptibility and biofilm production in Staphylococcus aureus isolated from white coats of health university students

Distal renal tubular acidosis: genetic causes and management

Interventions to obstructive long-term central venous catheter in cancer patients: a meta-analysis

Contribution of hip abductor–adductor muscles on static and dynamic balance of community-dwelling older adults

Evaluation of Portuguese limestones’ susceptibility to salt mist through laboratory testing

Microplastics cause neurotoxicity, oxidative damage and energy-related changes and interact with the bioaccumulation of mercury in the European seabass, Dicentrarchus labrax (Linnaeus, 1758)

Growth and metabolic parameters of common snook juveniles raised in freshwater with different water hardness

Exercise on balance and function for knee osteoarthritis: A randomized controlled trial

Completely illiterate adults can learn to decode in 3 months

Heat wave and cold spell changes in Iberia for a future climate scenario

Diphenyl diselenide protects against methylmercury‐induced inhibition of thioredoxin reductase and glutathione peroxidase in human neuroblastoma cells: a comparison with ebselen

Brain GLP-1/IGF-1 Signaling and Autophagy Mediate Exendin-4 Protection Against Apoptosis in Type 2 Diabetic Rats

The effects of a simultaneous cognitive or motor task on the kinematics of walking in older fallers and non-fallers

Immediate effects of an anchor system on the stability limit of individuals with chronic dizziness of peripheral vestibular origin

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