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The genetic variance of mortality rates in Drosophila melanogaster increases with age early in life, but declines at intermediate ages. A simulation study was done in order to evaluate two competing explanations for this age-specific pattern: (1) demographic heterogeneity, and (2) binomial sampling effects. The pattern can be explained by demographic heterogeneity among and within genotypes. In contrast,...
The purpose of this study was to investigate the effects of cohort size on maximum likelihood estimates of mortality parameters. Recent experimental investigations have stressed the importance of large cohorts for detecting leveling off of mortality rates at older ages. In the present study, emphasis was placed on evaluation of relatively small cohorts (about 150-300 individuals). Deaths were simulated...
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