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Phenolic extractives have been isolated from Douglas-fir sapwood and heartwood and identified by NMR and mass spectroscopy. Pinocembrin, [5,5 ]-bisdihydroquercetin and two lignans, pinoresinol and 2,3-dihydro-2-(4 -O-β-glucopyranosyl-3 -methoxyphenyl)-3-hydroxymethyl-5- (3-hydroxypropyl)-7-methoxy-benzofuran are reported for the first time in these tissues. The chemical structures of these phenolic...
An abundant network of hydrogen bonds between the peptide backbone and conserved residues of the MHC II molecules plays a major interacting role and contributes to the ability of the MHC II molecules to bind a wide range of peptides. As a result, we observed that retro-inverso analogs of T cell peptides in which the amide bond was reversed while the side chains retained a correct orientation, did...
The effects of various concentrations of 2-fluoro-2-deoxy-d-glucose (FDG) on the aerobic metabolism of glucose and the reciprocal effect of glucose on the metabolism of FDG in glucose-grown repressed Saccharomyces cerevisiae cells were studied at 30 o C in a standard pyrophosphate medium containing 5 x 10 7 cells/ml by 1 H-, 19 F-, 31 P-NMR and biochemical...
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