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The surface plasmon resonance (SPR) biosensor is a very powerful tool for studying binding mechanisms between all kinds of biomolecular species without the need of any tagging or labeling. However, application of SPR at present is largely confined to the laboratory environment and SPR biosensors are yet to be widely accepted by the point-of-care diagnostics industry. Despite its attractive label-free...
The numerical simulation of a novel white-light interferometric surface plasmon resonance (WLISPR) sensor with high sensitivity and wide dynamic range is presented. It is perceived that the use of a broadband polychromatic source might effectively enable wide dynamic surface plasmon detection scheme and at the same time achieving comparable phase detection sensitivity to conventional laser-based surface...
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