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We investigate surface sealing behavior of polymer hollow particles with an open hole on their surfaces during thermal annealing. A series of processes involving synthesis of polystyrene (PS) solid particles, their swelling with the use of a swelling solvent, and freeze-drying enable us to make hollow particles with a controllable structure including outer/inner diameter and surface hole size. Based...
This paper describes a new system for NIR light-triggered, localized release of drugs. The system consists of biocompatible/degradable poly(ε-caprolactone) (PCL)-based fibers having a core loaded with doxorubicin (DOX) and a sheath incorporated with indocyanine green (ICG) as a NIR-absorbing agent together with a biocompatible/degradable, phase-changeable fatty acid. Upon NIR irradiation, the photothermal...
This paper describes a simple, inexpensive method for the fabrication of non-spherical polymeric particles. This method involves the use of a mechanical rubbing-assisted colloidal crystal to generate a substrate with an array of dimples on its surface, followed by selectively depositing a polymer into the dimples. As a proof-of-concept experiment, we demonstrated the fabrication of poly(ε-caprolactone)...
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