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ObjectiveHeightened levels of sEcad are found in the serum of patients with cancer and correlate with an unfavorable prognosis and later‐stages of disease. In this study, we explored whether sEcad is elevated in human OPSCC specimens and FaDu cells. Additionally, we investigated sEcad‐EGFR and sEcad‐IGF‐1R interactions and performed a functional analysis of sEcad in OPSCC cancers.
Materials and MethodssEcad,...
Cells of the immune system produce a variety of neuropeptides or peptide hormones, either constitutively or upon induction, and possess specific neuropeptide receptors that display ligand-receptor interactions similar to those described in the central nervous system (CNS). These findings suggest that specific subsets of lymphoid cells can produce and respond to peptides previously thought to be principally...
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