Search results for: Kyong-Suk Jin

Items from 1 to 5 out of 5 results

article

Juniperus chinensis and the functional compounds, cedrol and widdrol, ameliorate α-melanocyte stimulating hormone-induced melanin formation in B16F10 cells

Kyong-Suk Jin, Ji Young Lee, Sook Kyung Hyun, Byung Woo Kim, more

Food Science and Biotechnology > 2015 > 24 > 2 > 611-618

Anti-melanogenic activities of Juniperus chinensis methanol extracts (JCM) and isolation of functional compounds were investigated. JCM possessed potent anti-oxidative and tyrosinase inhibitory activities. α-Melanocyte stimulating hormone (α-MSH)-induced melanogenesis and tyrosinase activity were inhibited by JCM in B16F10 cells. JCM also possessed potent scavenging activities against...

article

Betulinic acid isolated from Vitis amurensis root inhibits 3-isobutyl-1-methylxanthine induced melanogenesis via the regulation of MEK/ERK and PI3K/Akt pathways in B16F10 cells

Kyong-Suk Jin, You Na Oh, Sook Kyung Hyun, Hyun Ju Kwon, more

Food and Chemical Toxicology > 2014 > 68 > Complete > 38-43

Previously, betulinic acid was identified as one of the main compounds responsible for the anti-melanogenic effect in Vitis amurensis root. In this study, we investigated the precise mechanism underlying the anti-melanogenic activity of betulinic acid in B16F10 cells. Betulinic acid significantly attenuated 3-isobutyl-1-methylxanthine (IBMX)-induced melanin production by inhibiting tyrosinase, tyrosinase...

article

Luteolin inhibits inflammatory responses by downregulating the JNK, NF-κB, and AP-1 pathways in TNF-α activated HepG2 cells

Chung Mu Park, Kyong-Suk Jin, Chung Won Cho, Yong-Woo Lee, more

Food Science and Biotechnology > 2012 > 21 > 1 > 279-283

The inhibitory mechanism of luteolin on tumor necrosis factor (TNF)-α-induced inflammation was investigated in HepG2 cells. Luteolin significantly suppressed TNF-α-stimulated inducible nitric oxide synthase (iNOS) expression in a dose-dependent manner without cytotoxicity. Phosphorylation and nuclear translocation of both transcription factors, nuclear factor (NF)-κB and activator protein (AP)-1,...

article

Luteolin and chicoric acid synergistically inhibited inflammatory responses via inactivation of PI3K-Akt pathway and impairment of NF-κB translocation in LPS stimulated RAW 264.7 cells

Chung Mu Park, Kyong-Suk Jin, Yong-Woo Lee, Young Sun Song

European Journal of Pharmacology > 2011 > 660 > 2-3 > 454-459

Synergistic anti-inflammatory effects of luteolin and chicoric acid, two abundant constituents of the common dandelion (Taraxacum officinale Weber), were investigated in lipopolysaccharide (LPS) stimulated RAW 264.7 cells. Co-treatment with luteolin and chicoric acid synergistically reduced cellular concentrations of nitric oxide (NO) and prostaglandin E ₂ (PGE ₂ ) and also inhibited...

article

α-pinene triggers oxidative stress and related signaling pathways in A549 and HepG2 cells

Kyong-Suk Jin, Min-Ji Bak, Mira Jun, Ho-Jin Lim, more

Food Science and Biotechnology > 2010 > 19 > 5 > 1325-1332

The volatile organic compounds (VOCs) -dlimonene, α-pinene, and isoprene-are widely used in scented products including food flavorings, air fresheners, and cosmetics. The effects of these VOCs on cell viability, oxidative stress generation, and the related molecular events were investigated in A549 and HepG2 cells. α-Pinene induced cell death, reactive oxygen species (ROS) generation, and reporter...

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Keywords

LUTEOLIN (2)
JUNIPERUS CHINENSIS (1)
ACTIVATOR PROTEIN 1 (1)
ACTIVATOR PROTEIN-1 (AP-1) (1)
AKT (1)
ANTI-MELANOGENESIS (1)
ANTI-MELANOGENIC ACTIVITY (1)
ANTI-OXIDATIVE ACTIVITY (1)
BETULINIC ACID (1)
C-JUN N-TERMINAL KINASE (JNK) (1)
CHICORIC ACID (1)
CYTOTOXICITY (1)
FUNCTIONAL COMPOUND (1)
INDUCIBLE NITRIC OXIDE SYNTHASE (INOS) (1)
MEK/ERK (1)
NF-ΚB (1)
NUCLEAR FACTOR (NF)-ΚB (1)
OXIDATIVE STRESS (1)
PI3K/AKT (1)
SYNERGISTIC ACTIVITY (1)
VITIS AMURENSIS ROOT (1)
VOLATILE ORGANIC COMPOUND (1)
Α-PINENE (1)
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Springer (3)
Elsevier (2)

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Search results for: Kyong-Suk Jin

Juniperus chinensis and the functional compounds, cedrol and widdrol, ameliorate α-melanocyte stimulating hormone-induced melanin formation in B16F10 cells

Betulinic acid isolated from Vitis amurensis root inhibits 3-isobutyl-1-methylxanthine induced melanogenesis via the regulation of MEK/ERK and PI3K/Akt pathways in B16F10 cells

Luteolin inhibits inflammatory responses by downregulating the JNK, NF-κB, and AP-1 pathways in TNF-α activated HepG2 cells

Luteolin and chicoric acid synergistically inhibited inflammatory responses via inactivation of PI3K-Akt pathway and impairment of NF-κB translocation in LPS stimulated RAW 264.7 cells

α-pinene triggers oxidative stress and related signaling pathways in A549 and HepG2 cells

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