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The contribution of the pleural mesothelium to pleural liquid and protein transport is still vigorously debated. Recent in vitro studies of stripped pleural membrane and free-standing pericardium have demonstrated active ion solute coupled transport of liquid and transcytosis of protein. However, the relative contribution of the passive transport properties of the pleural mesothelium compared to the...
In tissue samples of rat diaphragm mounted between two chambers, we measured the flow of albumin solution (0-5 g/dl) containing radioactive tracer 125 I-albumin in response to a driving pressure of 20 cmH 2 O. The ratio of the albumin concentration of the output solution to that of the input (sieving ratio, C out /C in ) was measured from solution...
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