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Aim: To determine the frequency of chromosomal aberrations particularly 22q11 deletion in Indian children ≤2 years with different types of conotruncal malformations and their association with abnormal aortic arch. Additionally, extracardiac features were also studied.
Methods: Conventional cytogenetic and fluorescence in situ hybridization analyses were performed in 254 patients with conotruncal...
Monitoring of newborns at birth for clinically and cytogenetically observable malformations as well as a comprehensive Health Audit Survey are being carried out in the high-level natural radiation (HLNR) area of Kerala, a southwest state of India. A total of 92,689 newborns were monitored from August 1995 to June 2004 and overall incidence of stillbirths and malformations was 0.51% and 2.03%. Multiple...
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