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Here, we investigate the mechanism through which paraoxonase 1 (PON1) may regulate cholesterol efflux. Pretreatment of oxLDL with PON1 (oxLDL–PON1) contributed to the formation of LysoPC. In J774 macrophages, oxLDL–PON1 increased cholesterol efflux by more than 47% compared to oxLDL alone. oxLDL–PON1 significantly increased mRNA and protein expression of ABCA1 and ABCG1, as well as of PPARγ and LXRα...
This study describes the formation of emulsion-based materials with novel textural characteristics by controlled heteroaggregation of food-grade colloidal particles and polymers. Heteroaggregation was induced by mixing a suspension of colloidal particles (β-lactoglobulin-coated lipid droplets) with a solution of polymer molecules (pectin) under conditions where the particles and polymers had similar...
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